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9UBC image
Sub-Particle Structure Of The Iterative Acetyltransferase From Actinomycetes In Complex With Accoa And Monoacetylated Lasso Peptides
Organism: Actinosynnema mirum dsm 43827
Method: ELECTRON MICROSCOPY
Resolution:3.43 Å Release Date: 2026-02-25
Classification: TRANSFERASE
Ligands: ACO

9IY3 image
Iterative Acetyltransferase On Lasso Peptides From Actinomycetes In Complex With Coa

9IY4 image
Iterative Acetyltransferase On Lasso Peptides From Actinomycetes In Complex With Accoa

6DKB image
Crystal Structure Of Trk-A In Complex With The Pan-Trk Kinase Inhibitor, Compound 10B.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.68 Å Release Date: 2018-07-11
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: FKY

6DKG image
Crystal Structure Of Trk-A In Complex With The Pan-Trk Kinase Inhibitor, Compound 13B.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.53 Å Release Date: 2018-07-11
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 22L, GO7

6DKI image
Crystal Structure Of Trk-A In Complex With The Pan-Trk Kinase Inhibitor, Compound 19.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.11 Å Release Date: 2018-07-11
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 22L, GOD

6DKW image
Crystal Structure Of Trk-A In Complex With The Pan-Trk Kinase Inhibitor, Compound 3.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.91 Å Release Date: 2018-07-11
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: GXA

6D1Y image
Crystal Structure Of Tyrosine-Protein Kinase Receptor In Complex With 2,4-Dichloro-N-(3-Methyl-1-Phenyl-1H-Pyrazol-5-Yl)Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.93 Å Release Date: 2018-05-02
Classification: TRANSFERASE/Inhibitor
Ligands: FQJ

6D1Z image
Crystal Structure Of Tyrosine-Protein Kinase Receptor In Complex With 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.87 Å Release Date: 2018-05-02
Classification: TRANSFERASE/Inhibitor
Ligands: FQD, GOL, FQM

6D20 image
Crystal Structure Of Tyrosine-Protein Kinase Receptor In Complex With 5-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4(3H)-One And 5-{[2,4-Dichloro-5-(Pyridin-2-Yl)Benzene-1-Carbonyl]Amino}-N-(2-Hydroxy-2-Methylpropyl)-1-Phenyl-1H-Pyrazole-3-Carboxamide Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.94 Å Release Date: 2018-05-02
Classification: TRANSFERASE/Inhibitor
Ligands: FQD, FQG

6D22 image
Crystal Structure Of Tyrosine-Protein Kinase Receptor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.46 Å Release Date: 2018-05-02
Classification: TRANSFERASE

5KZ0 image
Structure Of Human Anaplastic Lymphoma Kinase In Complex With 2-[(1R)-1-{[2-Amino-5-(1,3-Dimethyl-1H-Pyrazol-4-Yl)Pyridin-3-Yl]Oxy}Ethyl]-4-Fluoro-N,N-Dimethylbenzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.30 Å Release Date: 2016-08-17
Classification: Transferase/Transferase Inhibitor
Ligands: 6YL

4CLI image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With Pf- 06463922 ((10R)-7-Amino-12-Fluoro-2,10,16-Trimethyl-15-Oxo-10,15,16, 17-Tetrahydro-2H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11) Benzoxadiazacyclotetradecine-3-Carbonitrile).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.05 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: 5P8

4CLJ image
Structure Of L1196M Mutant Human Anaplastic Lymphoma Kinase In Complex With Pf-06463922 ((10R)-7-Amino-12-Fluoro-2,10,16-Trimethyl- 15-Oxo-10,15,16,17-Tetrahydro-2H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11) Benzoxadiazacyclotetradecine-3-Carbonitrile).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.66 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: 5P8

4CMO image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 2-((1R)-1-((3-Amino-6-(2-Methoxypyridin-3-Yl)Pyrazin-2-Yl) Oxy)Ethyl)-4-Fluoro-N-Methylbenzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.05 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: YPW

4CMT image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 3-((1R)-1-(5-Fluoro-2-(2H-1,2,3-Triazol-2-Yl)Phenyl)Ethoxy)- 5-(3-(Methylsulfonyl)Phenyl)Pyridin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.73 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: GWH

4CMU image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor (10R)-7-Amino-12-Fluoro-1,3,10,16-Tetramethyl-16,17-Dihydro- 1H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11)Benzoxadiazacyclotetradecin-15(10H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.80 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: IV7

4CNH image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 3-((1R)-1-(5-Fluoro-2-Methoxyphenyl)Ethoxy)-5-(1-Methyl-1H- 1,2,3-Triazol-5-Yl)Pyridin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.90 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: 3U9

4CTB image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor (5R)-8-Amino-3-Fluoro-5,19-Dimethyl-20-Oxo-5,18,19,20- Tetrahydro-7,11-(Azeno)Pyrido(2',1':2,3)Imidazo(4,5-H)(2,5,11) Benzoxadiazacyclotetradecine-14-Carbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.79 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: KVC

4CTC image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 7-Amino-3-Cyclopropyl-12-Fluoro-1,10,16-Trimethyl-16,17- Dihydro-1H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11) Benzoxadiazacyclotetradecin-15(10H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.03 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: J99
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