Search Count: 27
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Amg 193, A Clinical Stage Mta-Cooperative Prmt5 Inhibitor, Drives Anti-Tumor Activity Preclinically And In Patients With Mtap-Deleted Cancers
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2024-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: GOL, DMS, A1ATH, MTA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: GOL, DMS, A1ATH, MTA
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Cryo-Em Structure Of Human Steap1 In Complex With Amg 509 Fab
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2023-11-22 Classification: membrane protein/immune system Ligands: LBN, FAD, HEM |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2023-11-22
Ligands: LBN, FAD, HEM
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Hmcl1 Inhibitor Complex
Organism: Homo sapiens
Method: SOLUTION NMR Release Date: 2019-05-22 Classification: APOPTOSIS/INHIBITOR Ligands: N8J |
Organism: Homo sapiens
Method: SOLUTION NMR
Release Date: 2019-05-22
Ligands: N8J
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Co-Crystal Structure Of Mcl1 With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2019-05-15 Classification: APOPTOSIS/INHIBITOR Ligands: LOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: LOD
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Co-Crystal Structure Of Mcl1 With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-05-15 Classification: APOPTOSIS/INHIBITOR Ligands: LOJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: LOJ
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Co-Crystal Structure Of Mcl1 With Inhibitor 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2019-05-15 Classification: APOPTOSIS/INHIBITOR Ligands: N0J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: N0J
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Crystal Structure Of Mcl1 With Inhibitor 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2019-05-15 Classification: APOPTOSIS/INHIBITOR Ligands: N0M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: N0M
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Crystal Structure Of Mcl1 With Inhibitor 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2019-05-15 Classification: APOPTOSIS Ligands: N0P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-15
Ligands: N0P
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Crystal Structure Of C-Met In Complex With Naphthyridinone Inhibitor 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2016-02-10 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5SZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: 5SZ
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Crystal Structure Of C-Met In Complex With Amg 337
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2016-02-10 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5T1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: 5T1
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Crystal Structure Of Sphk1 With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2013-07-24 Classification: Transferase/Transferase Inhibitor Ligands: 1V2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-24
Ligands: 1V2
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Crystal Structure Of The Vegfr2 Kinase Domain In Complex With A Pyridyl-Pyrimidine Benzimidazole Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2009-08-25 Classification: TRANSFERASE Ligands: K11, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-08-25
Ligands: K11, EDO
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Crystal Structure Of Human Jnk3 Complexed With N-(3-Methyl-4-(3-(2-(Methylamino)Pyrimidin-4-Yl)Pyridin-2-Yloxy)Naphthalen-1-Yl)-1H-Benzo[D]Imidazol-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2009-01-06 Classification: TRANSFERASE Ligands: BZ9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-01-06
Ligands: BZ9
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Structure Of Auroraa With Pyridyl-Pyrimidine Urea Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2008-12-23 Classification: Transferase/Inhibitor Ligands: AK8, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-12-23
Ligands: AK8, SO4
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Structure Of C-Met With Pyrimidone Inhibitor 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2008-10-07 Classification: TRANSFERASE Ligands: MT3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-10-07
Ligands: MT3
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Structure Of C-Met With Pyrimidone Inhibitor 50
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2008-10-07 Classification: TRANSFERASE Ligands: MT4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-10-07
Ligands: MT4
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Crystal Structure Of The Vegfr2 Kinase Domain In Complex With A 2,3-Dihydro-1,4-Benzoxazine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2008-04-08 Classification: TRANSFERASE Ligands: 2RL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-04-08
Ligands: 2RL
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Crystal Structure Of The Vegfr2 Kinase Domain In Complex With A Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2008-04-08 Classification: TRANSFERASE Ligands: RAJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-04-08
Ligands: RAJ
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Crystal Structure Of The Vegfr2 Kinase Domain In Complex With A Naphthamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2008-04-01 Classification: TRANSFERASE Ligands: 900 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-04-01
Ligands: 900
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Crystal Structure Of The Vegfr2 Kinase Domain In Complex With A Naphthamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2008-04-01 Classification: TRANSFERASE Ligands: EDO, 887 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-04-01
Ligands: EDO, 887