Search Count: 18
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ7
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ8, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ8, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ9
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: Q6K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: Q6K, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations. Compound 51 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1IUK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1IUK
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Crystal Structure Of Parp1 Catalytic Domain Bound To Azd5305 (Saruparib)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2024-12-04 Classification: TRANSFERASE Ligands: A1H63, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-04
Ligands: A1H63, SO4
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Crystal Structure Of Parp1 Catalytic Domain Bound To Azd9574
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2024-12-04 Classification: TRANSFERASE Ligands: A1H64, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-04
Ligands: A1H64, SO4
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2023-07-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, PQI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: MG, GDP, PQI
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.11 Å Release Date: 2023-07-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, PUO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: MG, GDP, PUO
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.18 Å Release Date: 2022-04-20 Classification: SIGNALING PROTEIN Ligands: V4T, MG, GDP, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-20
Ligands: V4T, MG, GDP, CA
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2022-04-20 Classification: SIGNALING PROTEIN Ligands: MG, GDP, V52, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-20
Ligands: MG, GDP, V52, CA
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2022-04-20 Classification: SIGNALING PROTEIN Ligands: MG, GDP, VLE, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-20
Ligands: MG, GDP, VLE, CA
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Parp1 Catalytic Domain In Complex With 8-Chloroquinazolinone-Based Inhibitor (Compound 9)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2021-09-15 Classification: TRANSFERASE Ligands: VKW, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-15
Ligands: VKW, SO4
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Parp1 Catalytic Domain In Complex With Isoquinolone-Based Inhibitor (Compound 16)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2021-09-15 Classification: TRANSFERASE Ligands: VKT, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-15
Ligands: VKT, SO4
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Parp1 Catalytic Domain In Complex With A Selective Pyridine Carboxamide-Based Inhibitor (Compound 22)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2021-09-15 Classification: TRANSFERASE Ligands: VKQ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-15
Ligands: VKQ, SO4
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.37 Å Release Date: 2020-02-26 Classification: SIGNALING PROTEIN Ligands: MG, GDP, O7K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-26
Ligands: MG, GDP, O7K, SO4
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.72 Å Release Date: 2020-02-19 Classification: SIGNALING PROTEIN Ligands: MG, GDP, MKW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-19
Ligands: MG, GDP, MKW
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.31 Å Release Date: 2020-02-19 Classification: SIGNALING PROTEIN Ligands: MG, GDP, MKZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-19
Ligands: MG, GDP, MKZ