Search Count: 31
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Discovery Of Mk-8189, A Highly Potent And Selective Pde10A Inhibitor For The Treatment Of Schizophrenia
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2023-02-08 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, S9I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-02-08
Ligands: ZN, MG, S9I
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Structure Of Human Hdac2 In Complex With Apicidin
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2021-05-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, PEG, YED |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-05
Ligands: ZN, CA, PEG, YED
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Structure Of Human Hdac2 In Complex With An Inhibitor That Lacks A Zinc Binding Group (Compound 12)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2021-05-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, ACT, PEG, YEM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-05
Ligands: ZN, CA, ACT, PEG, YEM
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Structure Of Human Hdac2 In Complex With An Inhibitor Lacking A Zinc Binding Group (Compound 19)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2021-05-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, SO4, CA, ACT, PEG, YEV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-05
Ligands: ZN, SO4, CA, ACT, PEG, YEV
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Sortilin-Progranulin Interaction With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2020-08-12 Classification: UNKNOWN FUNCTION Ligands: UMJ, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: UMJ, GOL
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Sortilin-Progranulin Interaction With Compound 17
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2020-08-12 Classification: UNKNOWN FUNCTION Ligands: UP4, UNL, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: UP4, UNL, GOL
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Sortilin-Progranulin Interaction With Compound 24
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2020-08-12 Classification: UNKNOWN FUNCTION Ligands: UOY, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: UOY, GOL
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Nmr Structure Of The La Module From Human Larp4A
Organism: Homo sapiens
Method: SOLUTION NMR Release Date: 2019-03-13 Classification: RNA BINDING PROTEIN |
Organism: Homo sapiens
Method: SOLUTION NMR
Release Date: 2019-03-13
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Crystal Structure Of The Prototype Foamy Virus Intasome With A 2- Pyridinone Aminal Inhibitor (Compound 18)
Organism: Human spumaretrovirus
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2017-03-29 Classification: TRANSFERASE/DNA/INHIBITOR Ligands: ZN, GOL, MG, SO4, 8G4 |
Organism: Human spumaretrovirus
Method: X-RAY DIFFRACTION
Release Date: 2017-03-29
Ligands: ZN, GOL, MG, SO4, 8G4
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Crystal Structure Of The Prototype Foamy Virus Intasome With A 2- Pyridinone Aminal Inhibitor (Compound 31)
Organism: Human spumaretrovirus
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2017-03-29 Classification: TRANSFERASE/DNA/INHIBITOR Ligands: ZN, GOL, MG, SO4, 8G1 |
Organism: Human spumaretrovirus
Method: X-RAY DIFFRACTION
Release Date: 2017-03-29
Ligands: ZN, GOL, MG, SO4, 8G1
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Structures Of The Human Ox1 Orexin Receptor Bound To Selective And Dual Antagonists
Organism: Homo sapiens, Pyrococcus abyssi (strain ge5 / orsay)
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2016-03-09 Classification: SIGNALING PROTEIN Ligands: SUV, OLA |
Organism: Homo sapiens, Pyrococcus abyssi (strain ge5 / orsay)
Method: X-RAY DIFFRACTION
Release Date: 2016-03-09
Ligands: SUV, OLA
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Structures Of The Human Ox1 Orexin Receptor Bound To Selective And Dual Antagonists
Organism: Homo sapiens, Pyrococcus abyssi (strain ge5 / orsay)
Method: X-RAY DIFFRACTION Resolution:2.83 Å Release Date: 2016-03-09 Classification: SIGNALING PROTEIN Ligands: 4OT, OLA |
Organism: Homo sapiens, Pyrococcus abyssi (strain ge5 / orsay)
Method: X-RAY DIFFRACTION
Release Date: 2016-03-09
Ligands: 4OT, OLA
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Pde10 Complexed With 5-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]Pyrazolo[1,5-A]Pyrimidin-7-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2016-01-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, 5AV, 4PX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: ZN, MG, 5AV, 4PX
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Pde10 Complexed With N-[(1-Methylpyrazol-4-Yl)Methyl]-5-[[(1S,2S)-2-(2-Pyridyl)Cyclopropyl]Methoxy]Pyrazolo[1,5-A]Pyrimidin-7-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2016-01-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, 5AY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: ZN, MG, 5AY
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Pde10 Complexed With6-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-2-[2-(2-Pyridyl)Ethoxy]Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-12-02 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4PX, 4Y1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-02
Ligands: ZN, MG, 4PX, 4Y1
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Crystal Structure Of The Prototype Foamy Virus Intasome With A 2-Pyridinone Aminal Inhibitor
Organism: Human spumaretrovirus
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2015-10-07 Classification: Transferase/DNA/Inhibitor Ligands: ZN, GOL, X2P, MG, SO4 |
Organism: Human spumaretrovirus
Method: X-RAY DIFFRACTION
Release Date: 2015-10-07
Ligands: ZN, GOL, X2P, MG, SO4
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Crystal Structure Of The Prototype Foamy Virus Intasome With A 2-Pyridinone Aminal Inhibitor
Organism: Human spumaretrovirus
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2015-10-07 Classification: transferase/DNA/inhibitor Ligands: ZN, GOL, MG, SO4, 4RT |
Organism: Human spumaretrovirus
Method: X-RAY DIFFRACTION
Release Date: 2015-10-07
Ligands: ZN, GOL, MG, SO4, 4RT
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Pde10 Complexed With 6-Chloro-N-[(2,4-Dimethylthiazol-5-Yl)Methyl]-5-Methyl-2-[3-(2-Quinolyl)Propoxy]Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2015-10-07 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4PX, 4XU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-07
Ligands: ZN, MG, 4PX, 4XU
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Pde10 Complexed With 4,6-Dichloro-2-Cyclopropyl-5-Methyl-Pyrimidine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XS
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Pde10 Complexed With 6-Chloro-2-Cyclopropyl-5-Methyl-Pyrimidin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2015-09-30 Classification: hydrolase/hydrolase inhibitor Ligands: ZN, MG, 4XV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: ZN, MG, 4XV