Search Count: 6
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And (2R)-4-(2,6-Dimethoxypyrimidin-4-Yl)-1-[(4-Ethylphenyl)Sulfonyl]-N-(4-Methoxybenzyl)Piperazine-2-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, SO4, 26S |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, SO4, 26S
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And (2R)-4-(2,6-Dimethoxypyrimidin-4-Yl)-N-(4-Methoxybenzyl)-1-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazine-2-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, SO4, 26F |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, SO4, 26F
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And (2R)-4-(6-Chloropyridazin-3-Yl)-N-(4-Methoxybenzyl)-1-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazine-2-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, 46F, SO4 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, 46F, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With (2E)-3-(4-{[(1-{[(13-Cyclohexyl-6-Oxo-6,7-Dihydro-5H-Indolo[1,2-D][1,4]Benzodiazepin-10-Yl)Carbonyl]Amino}Cyclopentyl)Carbonyl]Amino}Phenyl)Prop-2-Enoic Acid And N-Cyclopropyl-6-[(3R)-3-{[4-(Trifluoromethoxy)Benzyl]Carbamoyl}-4-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazin-1-Yl]Pyridazine-3-Carboxamide
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:3.22 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 23E, 63F, SO4 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 23E, 63F, SO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Genotype 1A Complex With N-Cyclopropyl-6-[(3R)-3-{[4-(Trifluoromethoxy)Benzyl]Carbamoyl}-4-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazin-1-Yl]Pyridazine-3-Carboxamide
Organism: Hepatitis c virus subtype 1a
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 63F, PO4 |
Organism: Hepatitis c virus subtype 1a
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 63F, PO4
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Genotype 1A Complex With N-[(2S)-Butan-2-Yl]-6-[(3R)-3-{[4-(Trifluoromethoxy)Benzyl]Carbamoyl}-4-{[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Piperazin-1-Yl]Pyridazine-3-Carboxamide
Organism: Hepatitis c virus subtype 1a
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2011-04-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 33F, GOL |
Organism: Hepatitis c virus subtype 1a
Method: X-RAY DIFFRACTION
Release Date: 2011-04-20
Ligands: 33F, GOL