Search Count: 43
 |
Crystal Structure Of Irak4-Hsa Complexed With N-[(2R)-2-Fluoro-3-Hydroxy-3-Methylbutyl]-6-[(5-Fluoropyri-Yl)Amino]-4-[(Propan-2-Yl)Amino]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZVD, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: ZVD, SO4
 |
Crystal Structure Of Irak4-Hsa Complexed With Bms-986126; 6-((5-Cyano-2-Pyrimidinyl)Amino)-N-((2R)-2-Fluoro-3-Hydroxhylbutyl)-4-(Isopropylamino)Nicotinamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZVG, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: ZVG, SO4
 |
Crystal Structure Of Irak4-Hsa Complexed With Bms-986147; 6-{5-Cyano-1H-Pyrazolo[3,4-B]Pyridin-1-Yl}-N-[(2R)-2-Fluorroxy-3-Methylbutyl]-4-[(Propan-2-Yl)Amino]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.76 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, ZVA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: SO4, ZVA
 |
Crystal Structure Of Human Tlr8 Ectodomain Bound To Small Molecule Antagonist 21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.76 Å Release Date: 2022-05-04 Classification: RNA BINDING PROTEIN Ligands: NAG, RQY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-05-04
Ligands: NAG, RQY
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-12 Aka:6-[(Cyclopropanecarbonyl)Amino]-4-{[2-Methoxy-3-(Pyrimidin-2-Yl)Phenyl]Amino}-N-Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2021-08-04 Classification: TRANSFERASE Ligands: VZJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-04
Ligands: VZJ
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-12 Aka:6-[(Cyclopropanecarbonyl)Amino]-4-({3-[6-(Dimethylcarbamoyl)Pyridazin-3-Yl]-2-Methoxyphenyl}Amino)-N-Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2021-08-04 Classification: TRANSFERASE Ligands: VZG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-04
Ligands: VZG
 |
Irak4 In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2020-11-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: EXF, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-11-25
Ligands: EXF, SO4
 |
Crystal Structure Of Human Tlr8 Ectodomain Bound To Small Molecule Antagonist 14C
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2020-08-12 Classification: RNA BINDING PROTEIN Ligands: NAG, QSM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: NAG, QSM
 |
Crystal Structure Of Rar-Related Orphan Receptor C In Complex With A Novel Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-08-12 Classification: TRANSCRIPTION/Agonist Ligands: V27 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: V27
 |
Crystal Structure Of Rar-Related Orphan Receptor C In Complex With A Potent, Selective And Orally Bioavailable Ror-Gamma-T Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2020-08-12 Classification: TRANSCRIPTION/AGONIST Ligands: VBG, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: VBG, SO4
 |
Crystal Structure Of Interleukin-1 Receptor-Associated Kinase 4 (Irak4-Wt) Complex With A Nicotinamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2020-06-24 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: R7S, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-24
Ligands: R7S, SO4
 |
Crystal Structure Of Rar-Related Orphan Receptor C (Nhis-Rorgt(244- 487)-L6-Src1(678-692)) In Complex With An Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2020-04-08 Classification: TRANSCRIPTION Ligands: R7V, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R7V, GOL
 |
Structure Of Human Pregnane X Receptor Ligand Binding Domain Bound Tethered With Src Co-Activator Peptide And Compound-3 Aka 1,1,1,3,3,3-Hexafluoro-2-{4-[1-(4- Luorobenzenesulfonyl)Cyclopentyl]Phenyl}Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2020-02-12 Classification: TRANSFERASE Ligands: L7D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-12
Ligands: L7D
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-6C Aka 6-((1-(4-Cyanopheny L)-2-Oxo-1,2-Dihydro-3-Pyridinyl)Amino)-N-Cyclopropyl-8-(M Ethylamino)Imidazo[1,2-B]Pyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-01-29 Classification: TRANSFERASE Ligands: KZJ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-29
Ligands: KZJ, SO4
 |
Crystal Structure Of Rar-Related Orphan Receptor C (Nhis- Rorgt(244-487)-L6-Src1(678-692)) In Complex With A Tricyclic Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2019-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: O5B, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-06
Ligands: O5B, GOL
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-11 Aka 6-Cyclopropaneamido-4-{[2-Methoxy-3-(1-Methyl-1H-1,2,4-Tri Azol-3-Yl)Phenyl]Amino}-N-(?H?)Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2019-07-31 Classification: TRANSFERASE Ligands: LB7, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: LB7, CL
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_29 Aka 6-[(5-Fluoro-4-Meth Ylpyridin-2-Yl)Amino]-4-({2-Methoxy-3-[(Pyridin-2-Ylmethyl )Carbamoyl]Phenyl}Amino)-N-Methylpyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2019-07-31 Classification: TRANSFERASE Ligands: LB4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: LB4
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_12 Aka 4-[(2-Methanesulfonylphenyl)Amino]-N-(H3)Methyl-6-[(Pyridin-2- Yl)Amino]Pyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.56 Å Release Date: 2019-07-31 Classification: TRANSFERASE Ligands: LAJ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: LAJ, SO4
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_5 Aka 4-[(2-Carbamoylphen Yl)Amino]-6-[(5-Fluoropyridin-2-Yl)Amino]-N-Methylpyridine -3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2019-07-24 Classification: TRANSFERASE Ligands: L8Y, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: L8Y, SO4
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_5 Aka 4-[(2-Carbamoylphen Yl)Amino]-6-[(5-Fluoropyridin-2-Yl)Amino]-N-Methylpyridine -3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2019-07-24 Classification: TRANSFERASE Ligands: L91, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: L91, SO4