Search Count: 30
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Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand (2R)-2-Amino-N-[3-(Difluorom Ethoxy)-4-(1,3-Oxazol-5-Yl)Phenyl]-4-Methylpentanamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2022-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: YFV, SO4, 5OI |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: YFV, SO4, 5OI
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Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand 2-(1-Amino-3-Methylbutyl)-6- (Pyridin-4-Yl)Quinoline-4-Carbonitrile
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2022-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5P6, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: 5P6, SO4
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Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand (2R)-2-Amino-N-[3-(Difluorom Ethoxy)-4-(1,3-Oxazol-5-Yl)Phenyl]-4-Methylpentanamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.59 Å Release Date: 2022-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5QI, PG6, SO4, YFV |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: 5QI, PG6, SO4, YFV
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Structure Of Human Pregnane X Receptor Ligand Binding Domain Bound Tethered With Src Co-Activator Peptide In Complex With (S,S)-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2020-09-23 Classification: NUCLEAR PROTEIN Ligands: QCG, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: QCG, GOL
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-(3-(1-(4-Chlorophenyl)Cyclopropyl) -[1,2,4]Triazolo[4,3-A]Pyridin-8-Yl)Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2018-12-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, HJG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: NAP, HJG
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Crystal Structure Of Murine 11B- Hydroxysteroiddehydrogenase Complexed With 2-(3-(1-(4- Chlorophenyl)Cyclopropyl)-[1,2,4]Triazolo[4,3-A]Pyridin-8- Yl)Propan-2-Ol
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2018-12-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, HJG, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: NAP, HJG, SO4
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-[2-(4-Fluorophenyl)-2-Adamantyl]-1-(3-Methoxyazetidin-1-Yl)Ethanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8K4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8K4
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 1-(3-Hydroxyazetidin-1-Yl)-2-[(2S,5R)-2-(4-Fluorophenyl)-5-Methoxyadamantan-2-Yl]Ethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8K7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8K7
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-[(1R,3S,5R,7S)-2-[4-(4-Fluorophenyl)Phenyl]-6-Hydroxyadamantan-2-Yl]-1-(3- Hydroxyazetidin-1-Yl)Ethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KA
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-(2-Benzyl-6-Hydroxyadamantan-2-Yl)-1-(3-Hydroxyazetidin-1-Yl)Ethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KD
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Crystal Structure Of 11Beta-Hsd1 Double Mutant (L262R, F278E) Complexed With 2-[(5R,7S)-6-Hydroxy-2-Phenyladamantan-2-Yl]-1-(3-Hydroxyazetidin-1-Yl)Ethan-1-One (Bms-816336)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KG
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Crystal Structure Of Murine 11Beta- Hydroxysteroiddehydrogenase Complexed With 2-[(5R,7S)-6-Hydroxy-2-Phenyladamantan-2-Yl]-1-(3-Hydroxyazetidin-1-Yl)Ethan-1-One (Bms-816336)
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2017-11-01 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 8KG, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2017-11-01
Ligands: NAP, 8KG, SO4
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Structure Of Human Pregnane X Receptor Ligand Binding Domain With Adnectin-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2015-02-11 Classification: IMMUNE SYSTEM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-11
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Structure Of Human Pregnane X Receptor Ligand Binding Domain Bound With Adnectin-1 And Compound-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.14 Å Release Date: 2015-02-04 Classification: TRANSCRIPTION Ligands: 40U |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-04
Ligands: 40U
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Structure Of Human Pregnane X Receptor Ligand Binding Domain With Compound-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2015-01-28 Classification: TRANSCRIPTION Ligands: GOL, 40U |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: GOL, 40U
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Crystal Structure Of The Human Pxr-Lbd In Complex With N-{(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-Hydroxy-3,3-Dimethylpiperidin-1-Yl]-3-Methyl-1-Oxobutan-2-Yl}-3-Hydroxy-3-Methylbutanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-08-27 Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor Ligands: 2Q4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-08-27
Ligands: 2Q4, GOL
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Crystal Structure Of 11B-Hsd1 Double Mutant (L262R, F278E) In Complex With (1S,4S)-4-[8-(2-Fluorophenoxy)[1,2,4]Triazolo[4,3-A]Pyridin-3-Yl]Bicyclo[2.2.1]Heptan-1-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2014-06-11 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 1EO, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-11
Ligands: NAP, 1EO, CL
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Crystal Structure Of 11B-Hsd1 Double Mutant (L262R, F278E) In Complex With 3-[1-(4-Chlorophenyl)Cyclopropyl]-8-(2-Fluorophenoxy)[1,2,4]Triazolo[4,3-A]Pyridine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2014-06-11 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 1EN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-11
Ligands: NAP, 1EN
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Crystal Structure Of 11B-Hsd1 Double Mutant (L262R, F278E) In Complex With 3-[1-(4-Chlorophenyl)Cyclopropyl]-8-Cyclopropyl[1,2,4]Triazolo[4,3-A]Pyridine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2014-06-11 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 1EQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-11
Ligands: NAP, 1EQ
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase Complex With Bms-791325 Also Known As (1Ar,12Bs)-8-Cyclohexyl-N-(Dimethylsulfamoyl)-11-Methoxy-1A-{[(1R,5S)-3-Methyl-3,8-Diazabicyclo[3.2.1]Oct-8-Yl]Carbonyl}-1,1A,2,12B-Tetrahydrocyclopropa[D]Indolo[2,1-A][2]Benzazepine-5-Carboxamide And 2-(4-Fluorophenyl)-N-Methyl-6-[(Methylsulfonyl)Amino]-5-(Propan-2-Yloxy)-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2014-03-19 Classification: transferase/transferase INHIBITOR Ligands: 2N7, 2N5, SO4, BOG |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2014-03-19
Ligands: 2N7, 2N5, SO4, BOG