Search Count: 39
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High-Resolution Structure Of Wild-Type E. Coli Thymidylate Synthase
Organism: Escherichia coli (strain k12)
Method: X-RAY DIFFRACTION Resolution:1.05 Å Release Date: 2019-01-30 Classification: TRANSFERASE Ligands: UMC, CB3, NA, EPE |
Organism: Escherichia coli (strain k12)
Method: X-RAY DIFFRACTION
Release Date: 2019-01-30
Ligands: UMC, CB3, NA, EPE
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Toxoplasma Gondii Ts-Dhfr In Complex With Selective Inhibitor 29
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2019-01-23 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: UMP, NDP, CB3, K9A, EDO |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2019-01-23
Ligands: UMP, NDP, CB3, K9A, EDO
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Toxoplasma Gondii Ts-Dhfr In Complex With Selective Inhibitor 3
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:3.50 Å Release Date: 2019-01-23 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: UMP, NDP, CB3, BOD |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2019-01-23
Ligands: UMP, NDP, CB3, BOD
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Crystal Structure Of Toxoplasma Gondii Ts-Dhfr Complexed With Nadph, Dump, Pddf, And 5-(4-Chlorophenyl)-6-Ethylpyrimidine-2,4-Diamine (Pyrimethamine)
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:3.20 Å Release Date: 2018-08-22 Classification: OXIDOREDUCTASE Ligands: UMP, NDP, CB3, CP6 |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2018-08-22
Ligands: UMP, NDP, CB3, CP6
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Crystal Structure Of Toxoplasma Gondii Ts-Dhfr Complexed With Nadph, Dump, Pddf, And 5-(4-(3-(2-Methoxypyrimidin-5-Yl)Phenyl)Piperazin-1-Yl)Pyrimidine-2,4-Diamine (Trc-2533)
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:3.50 Å Release Date: 2018-08-22 Classification: OXIDOREDUCTASE Ligands: UMP, NDP, CB3, BOD |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2018-08-22
Ligands: UMP, NDP, CB3, BOD
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Crystal Structure Of Toxoplasma Gondii Ts-Dhfr Complexed With Nadph, Dump, Pddf, And 5-(4-Phenylpiperazin-1-Yl)-6-Propylpyrimidine-2,4-Diamine (Trc-2528)
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:2.97 Å Release Date: 2018-08-22 Classification: OXIDOREDUCTASE Ligands: UMP, NDP, CB3, BOJ |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2018-08-22
Ligands: UMP, NDP, CB3, BOJ
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E. Coli Thymidylate Synthase Mutant I264Am
Organism: Escherichia coli
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2018-05-16 Classification: TRANSFERASE Ligands: CB3, UMP, UMC |
Organism: Escherichia coli
Method: X-RAY DIFFRACTION
Release Date: 2018-05-16
Ligands: CB3, UMP, UMC
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Crystal Structure Of Toxoplasma Gondii Ts-Dhfr Complexed With Nadph, Dump, Pddf And 5-(4-(3,4-Dichlorophenyl)Piperazin-1-Yl)Pyrimidine-2,4-Diamine (Trc-15)
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:3.13 Å Release Date: 2016-09-28 Classification: Oxidoreductase/Oxidoreductase inhibitor Ligands: UMP, NDP, CB3, 73X |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2016-09-28
Ligands: UMP, NDP, CB3, 73X
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Crystal Structure Of The Loop Truncated Toxoplasma Gondii Ts-Dhfr
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-10-09 Classification: OXIDOREDUCTASE, TRANSFERASE Ligands: UMP, CB3, FOL, NDP |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2013-10-09
Ligands: UMP, CB3, FOL, NDP
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Crystal Structure Of The Toxoplasma Gondii Ts-Dhfr
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION Resolution:3.52 Å Release Date: 2013-10-02 Classification: transferase, oxidoreductase Ligands: UMP, CB3, FOL, NDP |
Organism: Toxoplasma gondii
Method: X-RAY DIFFRACTION
Release Date: 2013-10-02
Ligands: UMP, CB3, FOL, NDP
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E. Coli Thymidylate Synthase Y209W Variant In Complex With Substrate And A Cofactor Analog
Organism: Escherichia coli
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2012-08-29 Classification: TRANSFERASE Ligands: UMC, CB3 |
Organism: Escherichia coli
Method: X-RAY DIFFRACTION
Release Date: 2012-08-29
Ligands: UMC, CB3
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Crystal Structure Of The Chts-Dhfr F207A Non-Active Site Mutant
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2010-06-02 Classification: OXIDOREDUCTASE Ligands: UMP, CB3, MTX, NDP |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2010-06-02
Ligands: UMP, CB3, MTX, NDP
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Crystal Structure Of The A287F Active Site Mutant Of Ts-Dhfr From Cryptosporidium Hominis
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.74 Å Release Date: 2008-08-19 Classification: OXIDOREDUCTASE Ligands: UMP, CB3, DHF, NDP |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2008-08-19
Ligands: UMP, CB3, DHF, NDP
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Crystal Structure Of The A287F/S290G Active Site Mutant Of Ts-Dhfr From Cryptosporidium Hominis
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:3.25 Å Release Date: 2008-08-19 Classification: OXIDOREDUCTASE Ligands: UMP, CB3, DHF, NDP |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2008-08-19
Ligands: UMP, CB3, DHF, NDP
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Crystal Structure Of The S290G Active Site Mutant Of Ts-Dhfr From Cryptosporidium Hominis
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2007-07-17 Classification: TRANSFERASE, OXIDOREDUCTASE Ligands: UMP, CB3, MTX, NDP |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2007-07-17
Ligands: UMP, CB3, MTX, NDP
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Y94F Mutant Of Thymidylate Synthase Bound To Thymidine-5'-Phosphate And 10-Propargyl-5,8-Dideazafolid Acid
Organism: Escherichia coli
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2006-05-02 Classification: TRANSFERASE Ligands: PO4, TMP, CB3 |
Organism: Escherichia coli
Method: X-RAY DIFFRACTION
Release Date: 2006-05-02
Ligands: PO4, TMP, CB3
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Cryptococcus Neoformans Thymidylate Synthase Complexed With Substrate And An Antifolate
Organism: Filobasidiella neoformans
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2005-12-06 Classification: TRANSFERASE Ligands: UMP, CB3 |
Organism: Filobasidiella neoformans
Method: X-RAY DIFFRACTION
Release Date: 2005-12-06
Ligands: UMP, CB3
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Leishmania Major Pteridine Reductase 1 In Complex With Nadp And Cb3717
Organism: Leishmania major
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2005-08-31 Classification: OXIDOREDUCTASE Ligands: NDP, CB3, EDO |
Organism: Leishmania major
Method: X-RAY DIFFRACTION
Release Date: 2005-08-31
Ligands: NDP, CB3, EDO
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Crystal Structure Of The Thymidylate Synthase R166Q Mutant
Organism: Escherichia coli
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2003-11-11 Classification: TRANSFERASE Ligands: SO4, CB3 |
Organism: Escherichia coli
Method: X-RAY DIFFRACTION
Release Date: 2003-11-11
Ligands: SO4, CB3
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Crystal Structure Of Dhfr-Ts From Cryptosporidium Hominis
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2003-11-11 Classification: OXIDOREDUCTASE, TRANSFERASE Ligands: UMP, CB3, FOL, NDP |
Organism: Cryptosporidium hominis
Method: X-RAY DIFFRACTION
Release Date: 2003-11-11
Ligands: UMP, CB3, FOL, NDP