Search Count: 21
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Structure Of Plasmepsin X (Pm10, Pmx) From Plasmodium Falciparum 3D7 In Complex With Ucb7362
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2022-10-19 Classification: HYDROLASE Ligands: TWU |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2022-10-19
Ligands: TWU
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm589 (Ethyl 3-Methyl-4-((4-(Trifluoromethyl)Benzo[D]Oxazol-7-Yl)Methyl)-1H-Pyrrole-2-Carboxylate)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XAJ, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XAJ, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm634 (3-Methyl-N-(1-(5-Methylisoxazol-3-Yl)Ethyl)-4-(4-(Trifluoromethyl)Benzyl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XBY, FMN, ORO, GOL |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XBY, FMN, ORO, GOL
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm697 (3-Methyl-N-(1-(5-Methylisoxazol-3-Yl)Ethyl)-4-(6-(Trifluoromethyl)-1H-Indol-3-Yl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XCD, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XCD, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm705 (N-(1-(1H-1,2,4-Triazol-3-Yl)Ethyl)-3-Methyl-4-(1-(6-(Trifluoromethyl)Pyridin-3-Yl)Cyclopropyl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XC7, FMN, ORO, MG |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XC7, FMN, ORO, MG
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm778 (3-Methyl-N-(1-(5-Methyl-1H-Pyrazol-3-Yl)Ethyl)-4-(1-(6-(Trifluoromethyl)Pyridin-3-Yl)Cyclopropyl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XCM, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XCM, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm782 (N-(1-(5-Cyano-1H-Pyrazol-3-Yl)Ethyl)-3-Methyl-4-(1-(6-(Trifluoromethyl)Pyridin-3-Yl)Cyclopropyl)-1H-Pyrrole-2-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XCV, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XCV, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm784 (3-(1-(3-Methyl-4-((6-(Trifluoromethyl)Pyridin-3-Yl)Methyl)-1H-Pyrrole-2-Carboxamido)Ethyl)-1H-Pyrazole-5-Carboxamide)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2021-05-19 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: XE7, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2021-05-19
Ligands: XE7, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm557
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2020-04-22 Classification: OXIDOREDUCTASE Ligands: RL7, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: RL7, FMN, ORO
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm483
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2020-04-22 Classification: OXIDOREDUCTASE Ligands: RLA, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: RLA, FMN, ORO
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Plasmodium Falciparum Dihydroorotate Dehydrogenase Dhodh In Complex With 3,6-Dimethyl-N-(4-(Trifluoromethyl)Phenyl)-(1,2)Oxazolo(5,4-D)Pyrimidin-4-Amine
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2018-09-19 Classification: FLAVOPROTEIN Ligands: FMN, ORO, F1T |
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: FMN, ORO, F1T
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm421
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2016-09-28 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: 78Z, FMN, ORO, LDA, GOL |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2016-09-28
Ligands: 78Z, FMN, ORO, LDA, GOL
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bounded With Dsm422 (Tetrahydro-2-Naphthyl And 2-Indanyl Triazolopyrimidine)
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.32 Å Release Date: 2016-05-18 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 5Y5, FMN, ORO, LDA |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2016-05-18
Ligands: 5Y5, FMN, ORO, LDA
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm265
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2015-07-29 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: D65, FMN, ORO, GOL |
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION
Release Date: 2015-07-29
Ligands: D65, FMN, ORO, GOL
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm265
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2015-07-29 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: D65, FMN, ORO |
Organism: Plasmodium falciparum (isolate 3d7)
Method: X-RAY DIFFRACTION
Release Date: 2015-07-29
Ligands: D65, FMN, ORO
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High Resolution Crystal Structure Of Human Dihydroorotate Dehydrogenase Bound With Dsm338 (N-[3,5-Difluoro-4-(Trifluoromethyl)Phenyl]-5-Methyl-2-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Amine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.23 Å Release Date: 2014-06-04 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: FMN, ORO, 2V6, ACY, GOL, NA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: FMN, ORO, 2V6, ACY, GOL, NA, SO4
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Rat Dihydroorotate Dehydrogenase Bound With Dsm338 (N-[3,5-Difluoro-4-(Trifluoromethyl)Phenyl]-5-Methyl-2-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Amine)
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2014-06-04 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: FMN, ORO, 2V6 |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: FMN, ORO, 2V6
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm338 (N-[3,5-Difluoro-4-(Trifluoromethyl)Phenyl]-5-Methyl-2-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Amine)
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2014-06-04 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 2V6, FMN, ORO, GOL, SO4 |
Organism: Plasmodium falciparum
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: 2V6, FMN, ORO, GOL, SO4
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Crystal Structure Of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound With Inhibitor Dsm267
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2011-07-06 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: D67, FMN, ORO |
Organism: Plasmodium falciparum 3d7
Method: X-RAY DIFFRACTION
Release Date: 2011-07-06
Ligands: D67, FMN, ORO
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Adamts1 In Complex With A Novel N-Hydroxyformamide Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2011-03-30 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: QGF, ZN, CD, NI, MG, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-03-30
Ligands: QGF, ZN, CD, NI, MG, NA