Search Count: 12
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Braf In Complex With N-(4-Methyl-3-(1-Methyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-5-Yl)Phenyl)-3-(Trifluoromethyl)Benzamide.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2019-10-23 Classification: transferase/transferase inhibitor Ligands: K7S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-23
Ligands: K7S
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Braf In Complex With N-(3-(2-(2-Hydroxyethoxy)-6-Morpholinopyridin-4-Yl)-4-Methylphenyl)-2-(Trifluoromethyl)Isonicotinamide (Lxh254)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2019-09-04 Classification: transferase/transferase inhibitor Ligands: K81 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-09-04
Ligands: K81
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Braf In Complex With N-(3-(Tert-Butyl)Phenyl)-4-Methyl-3-(6-Morpholinopyrimidin-4-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2017-06-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 92D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: 92D
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Braf In Complex With Raf709
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2017-06-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 92J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: 92J
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Design, Synthesis And Structure Activity Relationship Of Potent Pan-Pim Kinase Inhibitors Derived From The Pyridyl-Amide Scaffold
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2016-04-06 Classification: Transferase/Transferase Inhibitor Ligands: PEG, 6CB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-06
Ligands: PEG, 6CB
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Discovery Of Imidazo[1,2-A]-Pyridine Inhibitors Of Pan-Pi3 Kinases That Are Efficacious In A Mouse Xenograft Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2016-02-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: GOL, 5XV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: GOL, 5XV
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Identification Of N-(4-((1R,3S,5S)-3-Amino-5-Methylcyclohexyl)Pyridin-3-Yl)-6-(2,6-Difluorophenyl)-5-Fluoropicolinamide (Pim447), A Potent And Selective Proviral Insertion Site Of Moloney Murine Leukemia (Pim) 1,2 And 3 Kinase Inhibitor In Clinical Trials For Hematological Malignancies
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-11-11 Classification: Transferase/Transferase Inhibitor Ligands: 5H7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-11-11
Ligands: 5H7
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Pim1 Complexed With A Phenylcarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2013-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2HV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-06
Ligands: 2HV
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Pim1 Complexed With A Pyridylcarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2HW, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-06
Ligands: 2HW, GOL
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Pim1 Complexed With A Pyridylcarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2HX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-06
Ligands: 2HX
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Crystal Structure Of Pi3K Gamma With N6-(3,4-Dimethoxyphenyl)-2-Morpholino-[4,5'-Bipyrimidine]-2',6-Diamine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2012-08-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 13K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-29
Ligands: 13K, SO4
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Pim1 Complexed With A Novel 3,6-Disubstituted Indole At 2.6 Ang Resolution
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2011-10-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3T9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-12
Ligands: 3T9