Search Count: 23
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Crystal Structure Of Human Cyclic Gmp-Amp Synthase In Complex With Amppnp And Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2025-04-02 Classification: TRANSFERASE Ligands: A1AU3, GOL, MG, ANP, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-02
Ligands: A1AU3, GOL, MG, ANP, ZN
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Crystal Structure Of Human Cyclic Gmp-Amp Synthase In Complex With Amppnp And Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.47 Å Release Date: 2025-04-02 Classification: TRANSFERASE Ligands: MG, ZN, ANP, GOL, JUJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-02
Ligands: MG, ZN, ANP, GOL, JUJ
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Crystal Structure Of Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With Compound 5; 3-((2-((3-Chloro-4-Fluorophenyl)Amino)-2-Oxoethyl)Carbamoyl)Picolinic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2025-01-01 Classification: TRANSFERASE Ligands: ANP, A1BJH, ZN, MN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: ANP, A1BJH, ZN, MN
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Crystal Structure Of Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With Compound 36; (S)-(6,7-Dichloro-1-Methyl-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)(5-(2-Hydroxyethoxy)Pyrimidin-2-Yl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.25 Å Release Date: 2025-01-01 Classification: TRANSFERASE Ligands: ZN, A1BJA, ANP, MN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: ZN, A1BJA, ANP, MN
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Crystal Structure Of Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With Compound 23; (S)-1-(6,7-Dichloro-1-Methyl-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)-2-Methoxyethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2025-01-01 Classification: TRANSFERASE Ligands: ZN, A1BJD, ANP, MN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: ZN, A1BJD, ANP, MN
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Crystal Structure Of Murine Nf-Kappab Inducing Kinase (Nik) In Complex With Compound 1A
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2018-07-04 Classification: TRANSFERASE Ligands: SO4, ELZ |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-07-04
Ligands: SO4, ELZ
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Crystal Structure Of Murine Nf-Kappab Inducing Kinase (Nik) In Complex With Compound 2F
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.84 Å Release Date: 2018-07-04 Classification: TRANSFERASE Ligands: ELW |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-07-04
Ligands: ELW
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Itk Kinase Domain In Complex With Compound 1 N-{1-[(1,1-Dioxo-1-Thian-2-Yl)(Phenyl)Methyl]-1H- Pyrazol-4-Yl}-5,5-Difluoro-5A-Methyl-1H,4H,4Ah,5H,5Ah,6H-Cyclopropa[F]Indazole-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2015-04-29 Classification: TRANSFERASE/INHIBITOR Ligands: 3P6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-29
Ligands: 3P6
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Itk Kinase Domain In Complex With Inhibitor Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2015-01-14 Classification: Transferase/transferase inhibitor Ligands: 30T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-14
Ligands: 30T
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Itk Kinase Domain With Compound Gne-9822
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.71 Å Release Date: 2014-07-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2W6, P4G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-02
Ligands: 2W6, P4G
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Aurora A Kinase Domain With Compound 2 (N-[1-(3-Cyanobenzyl)-1H-Pyrazol-4-Yl]-6-(1H-Pyrazol-4-Yl)-1H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-07-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2VU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-02
Ligands: 2VU
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Itk Kinase Domain With Compound 1 (N-[1-(3-Cyanobenzyl)-1H-Pyrazol-4-Yl]-2H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.58 Å Release Date: 2014-06-04 Classification: transferase/transferase inhibitor Ligands: SO4, 2VT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: SO4, 2VT
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Itk Kinase Domain With Compound 11 (N-[1-(3-Cyanobenzyl)-1H-Pyrazol-4-Yl]-6-(1H-Pyrazol-4-Yl)-1H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2014-06-04 Classification: transferase/transferase inhibitor Ligands: 2VU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: 2VU
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Itk Kinase Domain With Compound 28 (N-{1-[(1S)-3-(Dimethylamino)-1-Phenylpropyl]-1H-Pyrazol-4-Yl}-6-(1H-Pyrazol-4-Yl)-1H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2014-06-04 Classification: transferase/transferase inhibitor Ligands: 2VV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: 2VV
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Itk Kinase Domain With Compound 27 (N-{1-[(1R)-3-(Dimethylamino)-1-Phenylpropyl]-1H-Pyrazol-4-Yl}-6-(1H-Pyrazol-4-Yl)-1H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2014-06-04 Classification: transferase/transferase inhibitor Ligands: 2VW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-06-04
Ligands: 2VW
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Discovery Of Doravirine, An Orally Bioavailable Non-Nucleoside Reverse Transcriptase Inhibitor Potent Against A Wide Range Of Resistant Mutant Hiv Viruses
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:2.58 Å Release Date: 2014-02-12 Classification: Transferase/Inhhibitor, Hydrolase/Inhhibitor Ligands: 2KW |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2014-02-12
Ligands: 2KW
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Back Pocket Flexibility Provides Group-Ii Pak Selectivity For Type 1 Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2014-02-12 Classification: transferase/transferase inhibitor Ligands: 7KC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-02-12
Ligands: 7KC
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Back Pocket Flexibility Provides Group-Ii Pak Selectivity For Type 1 Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2014-02-12 Classification: transferase/transferase inhibitor Ligands: 2OL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-02-12
Ligands: 2OL
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Back Pocket Flexibility Provides Group-Ii Pak Selectivity For Type 1 Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-02-12 Classification: transferase/transferase inhibitor Ligands: 2OL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-02-12
Ligands: 2OL
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Back Pocket Flexibility Provides Group-Ii Pak Selectivity For Type 1 Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2014-02-12 Classification: transferase/transferase inhibitor Ligands: 2OQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-02-12
Ligands: 2OQ