Search Count: 26
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Application Of Off-Rate Screening In The Identification Of Novel Pan-Isoform Inhibitors Of Pyruvate Dehydrogenase Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2017-02-22 Classification: TRANSFERASE Ligands: 7F9, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: 7F9, SO4
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Application Of Off-Rate Screening In The Identification Of Novel Pan-Isoform Inhibitors Of Pyruvate Dehydrogenase Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2017-02-22 Classification: SIGNALING PROTEIN Ligands: 7FX, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: 7FX, SO4
 |
Application Of Off-Rate Screening In The Identification Of Novel Pan-Isoform Inhibitors Of Pyruvate Dehydrogenase Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2017-02-22 Classification: TRANSFERASE Ligands: TF3, 7F9, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: TF3, 7F9, MG
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Application Of Off-Rate Screening In The Identification Of Novel Pan-Isoform Inhibitors Of Pyruvate Dehydrogenase Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2017-02-22 Classification: TRANSFERASE Ligands: 7FW, TF3, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: 7FW, TF3, CL
 |
Application Of Off-Rate Screening In The Identification Of Novel Pan-Isoform Inhibitors Of Pyruvate Dehydrogenase Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2017-02-22 Classification: TRANSFERASE Ligands: 7FV, TF3, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: 7FV, TF3, CL
 |
Application Of Off-Rate Screening In The Identification Of Novel Pan-Isoform Inhibitors Of Pyruvate Dehydrogenase Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2017-02-22 Classification: TRANSFERASE Ligands: 7FE, TF3, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: 7FE, TF3, CL
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Ver-246608, A Novel Pan-Isoform Atp Competitive Inhibitor Of Pyruvate Dehydrogenase Kinase, Disrupts Warburg Metabolism And Induces Context- Dependent Cytostasis In Cancer Cells
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2014-12-03 Classification: TRANSFERASE Ligands: TF3, MG, SZ6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: TF3, MG, SZ6
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Ver-246608, A Novel Pan-Isoform Atp Competitive Inhibitor Of Pyruvate Dehydrogenase Kinase, Disrupts Warburg Metabolism And Induces Context- Dependent Cytostasis In Cancer Cells
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.49 Å Release Date: 2014-12-03 Classification: TRANSFERASE Ligands: TF3, MG, 7TJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: TF3, MG, 7TJ
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Targetting Conserved Water Molecules: Design Of 4-Aryl-5-Cyanopyrrolo [2,3-D] Pyrimidine Hsp90 Inhibitors Using Fragment-Based Screening And Structure-Based Optimization
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2012-10-24 Classification: CHAPERONE Ligands: 42C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-24
Ligands: 42C
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Targeting Conserved Water Molecules: Design Of 4-Aryl-5-Cyanopyrrolo[2,3-D]Pyrimidine Hsp90 Inhibitors Using Fragment-Based Screening And Structure-Based Optimization
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2012-10-24 Classification: CHAPERONE Ligands: 2N6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-24
Ligands: 2N6
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Targeting Conserved Water Molecules: Design Of 4-Aryl-5-Cyanopyrrolo[2,3-D]Pyrimidine Hsp90 Inhibitors Using Fragment-Based Screening And Structure-Based Optimization
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2012-10-24 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 0TM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-24
Ligands: 0TM
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Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2009-07-28 Classification: CHAPERONE Ligands: MG, ZZ2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: MG, ZZ2
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Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2009-07-28 Classification: CHAPERONE Ligands: DMS, ZZ3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: DMS, ZZ3
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Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2009-07-28 Classification: CHAPERONE Ligands: MG, ZZ3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: MG, ZZ3
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Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2009-07-28 Classification: CHAPERONE Ligands: ZZ4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZZ4
 |
Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2009-07-28 Classification: CHAPERONE Ligands: ZZ5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZZ5
 |
Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2009-07-28 Classification: CHAPERONE Ligands: ZZ6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZZ6
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Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2009-07-28 Classification: CHAPERONE Ligands: 2KL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: 2KL
 |
4,5 Diaryl Isoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2007-12-11 Classification: CHAPERONE Ligands: 2GJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-12-11
Ligands: 2GJ
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4,5 Diaryl Isoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2007-12-11 Classification: CHAPERONE Ligands: 2EQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-12-11
Ligands: 2EQ