Search Count: 22
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Egfr Exon20 Insertion Mutant Asv Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, CL, EDO, GOL, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS, CL, EDO, GOL, PEG
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Egfr Exon20 Insertion Mutant Svd Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS, EDO, GOL
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Egfr Exon20 Insertion Mutant Svd Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1A4E, CL, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1A4E, CL, EDO, GOL
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Wildtype Egfr Bound With (R)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.12 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN Ligands: A1ILZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1ILZ
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Egfr Exon20 Insertion Mutant Npg Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: A1IMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS
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Egfr Exon20 Insertion Mutant Npg Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2025-05-14 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
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Wild-Type Egfr Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: CL, A1IMT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: CL, A1IMT
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Egfr Exon20 Insertion Mutant Npg Bound With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2025-01-29 Classification: TRANSFERASE Ligands: A1IEZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: A1IEZ
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Egfr Exon20 Insertion Mutant Npg Bound With Compound 39
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2025-01-29 Classification: TRANSFERASE Ligands: EDO, A1IE0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: EDO, A1IE0
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Wildtype Egfr Bound With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2025-01-29 Classification: ONCOPROTEIN Ligands: DTT, A1IEZ, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: DTT, A1IEZ, CL
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Crystal Structure Of Human Clk1 Kinase In Complex With Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: SO4, XQX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: SO4, XQX
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Crystal Structure Of Human Acvr1 (Alk2) Kinase In Complex With Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: SO4, XQX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: SO4, XQX
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Nf-Kappa-B1 Bound With A Covalent Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2024-04-24 Classification: TRANSCRIPTION Ligands: JMR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-04-24
Ligands: JMR
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Stx-478, A Mutant-Selective, Allosteric Inhibitor Bound To Pi3Kalpha
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.11 Å Release Date: 2023-09-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: X3N, ZWE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-09-06
Ligands: X3N, ZWE
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Stx-478, A Mutant-Selective, Allosteric Inhibitor Bound To H1047R Pi3Kalpha
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.93 Å Release Date: 2023-09-06 Classification: TRANSFERASE/TRANSFERSE INHIBITOR Ligands: EDO, X3N, ZWE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-09-06
Ligands: EDO, X3N, ZWE
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Crystal Structure Of Egfr Lrtm With Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2022-07-27 Classification: SIGNALING PROTEIN Ligands: GOL, QCR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-07-27
Ligands: GOL, QCR
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Crystal Structure Of Egfr Lrtm With Compound 24
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2022-07-27 Classification: SIGNALING PROTEIN Ligands: GOL, QFO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-07-27
Ligands: GOL, QFO
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Crystal Structure Of Fgfr4 With An Irreversible Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.71 Å Release Date: 2015-04-01 Classification: Transferase/Transferase Inhibitor Ligands: SO4, 40M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-01
Ligands: SO4, 40M
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Crystal Structure Of Pim-1 Kinase Domain In Complex With 2-Methyl-5-Phenylfuran-3-Carboxylic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2015-01-14 Classification: TRANSFERASE Ligands: 2D2, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-14
Ligands: 2D2, GOL
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Pi3 Kinase Gamma With A Benzofuranone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.87 Å Release Date: 2010-06-09 Classification: TRANSFERASE Ligands: WYF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-06-09
Ligands: WYF