Search Count: 15
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Discovery Of A Small Molecule Itk And Pan-Trk Kinase Inhibitor (Pf-07245303) For The Potential Topical Treatment Of Atopic Dermatitis
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2025-11-19 Classification: SIGNALING PROTEIN Ligands: A1B66 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-19
Ligands: A1B66
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Human Retenoid-Related Orphan Receptor-Gamma (Rorc2) Ligand-Binding Domain In Complex With Compound 5 Andindazole Acid Bound In H12-Pocket
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2023-03-01 Classification: DNA BINDING PROTEIN Ligands: LKY, 4Y5, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-03-01
Ligands: LKY, 4Y5, SO4
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Human Retenoid-Related Orphan Receptor-Gamma (Rorc2) Ligand-Binding Domain In Complex With Compound 6A Andindazole Acid Bound In H12-Pocket
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2023-03-01 Classification: DNA BINDING PROTEIN Ligands: XNR, 4Y5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-03-01
Ligands: XNR, 4Y5
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Human Retenoid-Related Orphan Receptor-Gamma (Rorc2) Ligand-Binding Domain In Complex With Compound 8 Andindazole Acid Bound In H12-Pocket
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2023-03-01 Classification: DNA BINDING PROTEIN Ligands: XO5, XNX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-03-01
Ligands: XO5, XNX
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Discovery Of A High Affinity Inhibitor Of Cgas
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.23 Å Release Date: 2018-12-19 Classification: transferase/transferase inhibitor Ligands: ZN, KHM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: ZN, KHM
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Discovery Of A High Affinity Inhibitor Of Cgas
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2017-09-27 Classification: transferase/transferase inhibitor Ligands: ZN, 8ZM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 8ZM
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Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With 2',2'-Cgamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.22 Å Release Date: 2017-09-27 Classification: TRANSFERASE Ligands: ZN, 1YC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 1YC
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Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With 2',3'-Cgamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2017-09-27 Classification: TRANSFERASE Ligands: ZN, SO4, 1SY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, SO4, 1SY
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Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With 2',5'-Gpap
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.25 Å Release Date: 2017-09-27 Classification: TRANSFERASE Ligands: ZN, 9BG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 9BG
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Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With 3',3'-Cdimp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.04 Å Release Date: 2017-09-27 Classification: TRANSFERASE Ligands: ZN, 9B7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 9B7
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Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With 3',3'-Cdump
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.77 Å Release Date: 2017-09-27 Classification: TRANSFERASE Ligands: ZN, 9BJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 9BJ
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Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With 3',3'-Cgamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.58 Å Release Date: 2017-09-27 Classification: TRANSFERASE Ligands: ZN, 4BW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 4BW
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Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With Compound F2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.73 Å Release Date: 2017-09-27 Classification: TRANSFERASE Ligands: ZN, 9BS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 9BS
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Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With Compound F3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2017-09-27 Classification: TRANSFERASE Ligands: ZN, 9BV, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 9BV, SO4
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Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With Compound F1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.71 Å Release Date: 2017-09-27 Classification: TRANSFERASE Ligands: ZN, 9BY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 9BY