Search Count: 12
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Amg 193, A Clinical Stage Mta-Cooperative Prmt5 Inhibitor, Drives Anti-Tumor Activity Preclinically And In Patients With Mtap-Deleted Cancers
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2024-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: GOL, DMS, A1ATH, MTA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: GOL, DMS, A1ATH, MTA
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Crystal Structure Of Bace1 In Complex With (Z)-Fluoro-Olefin Containing Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2020-06-03 Classification: HYDROLASE/HYDROLASE Inhibitor Ligands: U64, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-03
Ligands: U64, IOD
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Co-Crystal Structure Of Bace With Inhibitor Am-6494
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2019-10-23 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: IOD, GOL, P6J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-23
Ligands: IOD, GOL, P6J
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Human Gkrp Bound To Amg2882 And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2015-05-13 Classification: sugar binding protein/inhibitor Ligands: 2WY, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-13
Ligands: 2WY, S6P, IOD, GOL, SO4
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Human Gkrp Bound To Amg-3295 And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.43 Å Release Date: 2015-05-13 Classification: sugar binding protein/inhibitor Ligands: 2WX, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-13
Ligands: 2WX, S6P, IOD, GOL, SO4
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Human Gkrp Bound To Amg-0696 And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2015-05-13 Classification: sugar binding protein/inhibitor Ligands: 2WZ, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-13
Ligands: 2WZ, S6P, IOD, GOL, SO4
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Human Gkrp Bound To Amg-0265 (N-[(R)-(2-Chlorophenyl){7-[4-(2-Hydroxypropan-2-Yl) Pyridin-2-Yl]-1-Benzothiophen-2-Yl}Methyl]Cyclopropanesulfonamide) And Sorbitol-6-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2015-03-18 Classification: transferase/transferase inhibitor Ligands: 2Y6, S6P, IOD, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-18
Ligands: 2Y6, S6P, IOD, GOL, SO4
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Crystal Structure Of Pde10A With 1H-Benzimidazol-2-Yl(4-((3-(Tetrahydro-2H-Pyran-4-Yl)-2-Pyridinyl)Oxy)Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2014-08-06 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, SO4, 2W1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-08-06
Ligands: ZN, SO4, 2W1
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Crystal Structure Of Pka With Compound 36
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2011-01-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: L9L |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-01-19
Ligands: L9L
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Crystal Structure Of Pkab3 (Pka Triple Mutant V123A, L173M, Q181K) With Compound 18
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2011-01-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: L9M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-01-19
Ligands: L9M
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Crystal Structure Of Pkab3 (Pka Triple Mutant V123A, L173M, Q181K) With Compound 27
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2011-01-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: L9N |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-01-19
Ligands: L9N
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Crystal Structure Of Mdm2 With Chromenotriazolopyrimidine 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2009-11-17 Classification: LIGASE Ligands: YIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-11-17
Ligands: YIN