Search Count: 20
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Structure Of P110 Alpha Bound To (S)-1-(4-((2-(4-(4-(2-Amino-4-(Difluoromethyl)Pyrimidin-5-Yl)-6-(3-Methylmorpholino)-1,3,5- Triazin-2-Yl)Piperazin-1-Yl)-2-Oxoethoxy)Methyl)Piperidin-1-Yl)Prop-2-En-1-One (Compound 9)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2024-08-28 Classification: TRANSFERASE/Inhibitor Ligands: RNX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-28
Ligands: RNX
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Structure Of Pik3Ca With Covalent Inhibitor 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2022-04-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2Q7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-06
Ligands: 2Q7
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Structure Of Pik3Ca With Covalent Inhibitor 22
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2022-04-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2IX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-06
Ligands: 2IX
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Gedatolisib Bound To The Pi3Kg Catalytic Subunit P110 Gamma
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2021-03-17 Classification: TRANSFERASE Ligands: VL1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-17
Ligands: VL1
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Ipi-549 Bound To The Pi3Kg Catalytic Subunit P110 Gamma
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2021-03-17 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: V7Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-17
Ligands: V7Y
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Nvs-Pi3-4 Bound To The Pi3Kg Catalytic Subunit P110 Gamma
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.15 Å Release Date: 2021-03-17 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: VLV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-17
Ligands: VLV
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Pqr530 [(S)-4-(Difluoromethyl)-5-(4-(3-Methylmorpholino)-6-Morpholino-1,3,5-Triazin-2-Yl)Pyridin-2-Amine] Bound To The Pi3Ka Catalytic Subunit P110Alpha
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.15 Å Release Date: 2019-06-26 Classification: TRANSFERASE Ligands: M1J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-06-26
Ligands: M1J
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Trypanosoma Brucei Ptr1 In Complex With Cycloguanil
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2019-05-08 Classification: OXIDOREDUCTASE Ligands: NAP, 1CY, ACT, GOL, DMS |
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION
Release Date: 2019-05-08
Ligands: NAP, 1CY, ACT, GOL, DMS
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Trypanosoma Brucei Ptr1 In Complex With The Triazine Inhibitor 1 (F217)
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2019-05-08 Classification: OXIDOREDUCTASE Ligands: NAP, GFE, ACT, GOL |
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION
Release Date: 2019-05-08
Ligands: NAP, GFE, ACT, GOL
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Trypanosoma Brucei Ptr1 In Complex With The Triazine Inhibitor 2A (F219).
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2019-05-08 Classification: OXIDOREDUCTASE Ligands: NAP, GJQ |
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION
Release Date: 2019-05-08
Ligands: NAP, GJQ
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Pqr309 - A Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I Pi3K/Mtor Inhibitor As Clinical Candidate In Oncology
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2017-09-06 Classification: TRANSFERASE Ligands: A3W, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: A3W, SO4
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Leishmania Major Pteridine Reductase 1 (Ptr1) In Complex With Compound 3
Organism: Leishmania major
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2017-05-03 Classification: OXIDOREDUCTASE Ligands: 6J6, NDP, GOL, ACT, PGE, EDO |
Organism: Leishmania major
Method: X-RAY DIFFRACTION
Release Date: 2017-05-03
Ligands: 6J6, NDP, GOL, ACT, PGE, EDO
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Trypanosoma Brucei Pteridine Reductase 1 (Ptr1) In Complex With Compound 1
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2017-03-22 Classification: OXIDOREDUCTASE Ligands: NAP, 6QT, ACT |
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: NAP, 6QT, ACT
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Leishmania Major Pteridine Reductase 1 (Ptr1) In Complex With Compound 1
Organism: Leishmania major
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2017-03-22 Classification: OXIDOREDUCTASE Ligands: 6QT, NDP, GOL, ACT, PEG, PGE, EDO |
Organism: Leishmania major
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 6QT, NDP, GOL, ACT, PEG, PGE, EDO
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Enterococcus Faecalis Thymidylate Synthase Complex With Methotrexate
Organism: Enterococcus faecalis
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2016-09-28 Classification: TRANSFERASE Ligands: SO4, MTX |
Organism: Enterococcus faecalis
Method: X-RAY DIFFRACTION
Release Date: 2016-09-28
Ligands: SO4, MTX
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Trypanosoma Brucei Ptr1 In Complex With Inhibitor Nmt-H037 (Compound 7)
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2016-08-17 Classification: OXIDOREDUCTASE Ligands: NAP, ACT, 6JM |
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION
Release Date: 2016-08-17
Ligands: NAP, ACT, 6JM
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Trypanosoma Brucei Ptr1 In Complex With Inhibitor Np-29
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2016-08-17 Classification: OXIDOREDUCTASE Ligands: NAP, CC6, ACT, GOL |
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION
Release Date: 2016-08-17
Ligands: NAP, CC6, ACT, GOL
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Trypanosoma Brucei Ptr1 In Complex With Inhibitor Np-13 (Hesperetin)
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2016-08-17 Classification: OXIDOREDUCTASE Ligands: NAP, 6JP, ACT, GOL |
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION
Release Date: 2016-08-17
Ligands: NAP, 6JP, ACT, GOL
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Trypanosoma Brucei Ptr1 In Complex With Cofactor And Inhibitor Nmt-H024 (Compound 2)
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION Resolution:1.38 Å Release Date: 2016-08-17 Classification: OXIDOREDUCTASE Ligands: NAP, ACT, 6JO |
Organism: Trypanosoma brucei brucei
Method: X-RAY DIFFRACTION
Release Date: 2016-08-17
Ligands: NAP, ACT, 6JO
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Etherocomplex Of Enteroccocus Faecalis Thymidylate Synthase With 5-Hydroxymethilene-6-Hydrofolic Acid And The Phtalimidic Inhibitor Ss7
Organism: Enterococcus faecalis
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2014-12-31 Classification: transferase/transferase inhibitor Ligands: SO4, THF, EDO, SS7 |
Organism: Enterococcus faecalis
Method: X-RAY DIFFRACTION
Release Date: 2014-12-31
Ligands: SO4, THF, EDO, SS7