Search Count: 20
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Discovery And Development Of A Novel Inhaled Antivirulence Therapy For The Treatment Of Pseudomonas Aeruginosa Infections In Patients With Chronic Respiratory Disease
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION Resolution:2.74 Å Release Date: 2022-12-21 Classification: HYDROLASE Ligands: ZN, CI8, CA |
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION
Release Date: 2022-12-21
Ligands: ZN, CI8, CA
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2022-11-23 Classification: HYDROLASE Ligands: ZN, 8IY |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 98O |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 99I |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 9DO |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 9A1 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 9B9 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Escherichia coli (strain k12)
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7PX |
Organism: Escherichia coli (strain k12)
Method: X-RAY DIFFRACTION
Release Date: 2022-09-07
Ligands: ZN, 7PX
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7PX |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7S6 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7S2 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7T5, EDO |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7TF |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 6G8 |
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Crystal Structure Of Hpk1 In Complex With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2YE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2YE
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Crystal Structure Of Hpk1 In Complex With Gne1858
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: F97, EDO, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: F97, EDO, MES
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Crystal Structure Of Hpk1 In Complex With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2WI, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2WI, SO4
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Crystal Structure Of Hpk1 In Complex With Compound 17
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2TR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2TR
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Benzothiophene Inhibitors Of Factor Ixa
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2010-02-23 Classification: Hydrolase/Hydrolase Inhibitor Ligands: IYX, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-23
Ligands: IYX, CA
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Selective Benzothiophine Inhibitors Of Factor Ixa
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.62 Å Release Date: 2010-02-23 Classification: Hydrolase/Hydrolase Inhibitor Ligands: CA, IZX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-23
Ligands: CA, IZX