Search Count: 18
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Estrogen Receptor Mutant L536S
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2019-11-27 Classification: TRANSCRIPTION Ligands: L5B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-27
Ligands: L5B
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.99 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: EUT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: EUT
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, RBQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: SO4, RBQ
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2014-11-26 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.83 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, GOL, UJB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: SO4, GOL, UJB
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, 7A5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: SO4, 7A5
 |
Discovery And Optimization Of Pyrimidone Indoline Amide Pi3Kbeta Inhibitors For The Treatment Of Phosphatase And Tensin Homologue (Pten)-Deficient Cancers
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-01-15 Classification: TRANSFERASE Ligands: J82 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2014-01-15
Ligands: J82
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Tricyclic Series Of Hsp90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.32 Å Release Date: 2011-10-26 Classification: CHAPERONE Ligands: YK9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-26
Ligands: YK9
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Tricyclic Series Of Hsp90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.61 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YJW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-19
Ligands: YJW
 |
Tricyclic Series Of Hsp90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YJX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-19
Ligands: YJX
 |
Tricyclic Series Of Hsp90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YJW, YJX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-19
Ligands: YJW, YJX
 |
Tricyclic Series Of Hsp90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-19
Ligands: YKB
 |
Tricyclic Series Of Hsp90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-19
Ligands: YKC
 |
Tricyclic Series Of Hsp90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-19
Ligands: YKE
 |
Tricyclic Series Of Hsp90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-19
Ligands: YKI
 |
Tricyclic Series Of Hsp90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.46 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-19
Ligands: YKJ
 |
Wild-Type Hydroxycinnamoyl-Coa Hydratase Lyase In Complex With Acetyl- Coa And Vanillin
Organism: Pseudomonas fluorescens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2008-05-27 Classification: LYASE Ligands: ACO, V55 |
Organism: Pseudomonas fluorescens
Method: X-RAY DIFFRACTION
Release Date: 2008-05-27
Ligands: ACO, V55
 |
A Ternary Complex Of Hydroxycinnamoyl-Coa Hydratase-Lyase (Hchl) With Acetyl-Coenzyme A And Vanillin Gives Insights Into Substrate Specificity And Mechanism.
Organism: Pseudomonas fluorescens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2008-05-27 Classification: LYASE Ligands: ACO, V55 |
Organism: Pseudomonas fluorescens
Method: X-RAY DIFFRACTION
Release Date: 2008-05-27
Ligands: ACO, V55