Search Count: 18
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2019-11-27 Classification: TRANSCRIPTION Ligands: L5B |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.99 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: EUT |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, RBQ |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2014-11-26 Classification: TRANSFERASE |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.83 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, GOL, UJB |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, 7A5 |
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Discovery And Optimization Of Pyrimidone Indoline Amide Pi3Kbeta Inhibitors For The Treatment Of Phosphatase And Tensin Homologue (Pten)-Deficient Cancers
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-01-15 Classification: TRANSFERASE Ligands: J82 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.32 Å Release Date: 2011-10-26 Classification: CHAPERONE Ligands: YK9 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.61 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YJW |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YJX |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YJW, YJX |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKB |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKC |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKE |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKI |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.46 Å Release Date: 2011-10-19 Classification: CHAPERONE Ligands: YKJ |
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Wild-Type Hydroxycinnamoyl-Coa Hydratase Lyase In Complex With Acetyl- Coa And Vanillin
Organism: Pseudomonas fluorescens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2008-05-27 Classification: LYASE Ligands: ACO, V55 |
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A Ternary Complex Of Hydroxycinnamoyl-Coa Hydratase-Lyase (Hchl) With Acetyl-Coenzyme A And Vanillin Gives Insights Into Substrate Specificity And Mechanism.
Organism: Pseudomonas fluorescens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2008-05-27 Classification: LYASE Ligands: ACO, V55 |