Search Count: 68
 |
Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT
 |
Structure Of Kras G12C Bound To Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: A1CQ2, GDP, MG
 |
Structure Of Kras G12C Bound To Divarasib (Gdc6036)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: GDP, MG, DMS, EDO, A1AWR, PEG
 |
Protac-Induced Ire1 Ternary Complex
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Resolution:2.60 Å Release Date: 2025-11-05 Classification: TRANSFERASE Ligands: A1BWF |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2025-11-05
Ligands: A1BWF
 |
Crystal Structure Of Selective Ire1A Inhibitor 29 At The Enzyme Active Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.43 Å Release Date: 2024-05-29 Classification: TRANSFERASE/INHIBITOR Ligands: EDO, XOE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-05-29
Ligands: EDO, XOE
 |
Crystal Structure Of Ire1A In Complex With G-6904
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2021-04-21 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: N8S, EPE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-21
Ligands: N8S, EPE
 |
Crystal Structure Of Ire1 In Complex With G-3053
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2021-04-21 Classification: TRANSFERASE/INHIBITOR Ligands: N97 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-21
Ligands: N97
 |
Crystal Structure Of Ire1A In Complex With G-4100
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.54 Å Release Date: 2021-04-21 Classification: TRANSFERASE/TRANSFERASE INHIBITOR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-21
 |
Structure Of Unphosphorylated Ire1 In Complex With G-1749
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2020-12-09 Classification: TRANSFERASE Ligands: SJG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-09
Ligands: SJG
 |
Structure Of Unphosphorylated Ire1 In Complex With G-7658
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2020-12-09 Classification: TRANSFERASE Ligands: SJM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-09
Ligands: SJM
 |
Structure Of Apo Unphosphorylated Ire1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.57 Å Release Date: 2020-12-09 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-09
 |
Structure Of Phosphorylated Apo Ire1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2020-12-09 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-09
 |
Structure Of Phosphorylated Ire1 In Complex With G-0701
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.74 Å Release Date: 2020-12-09 Classification: TRANSFERASE Ligands: SJV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-09
Ligands: SJV
 |
Structure Of Unphosphorylated Human Ire1 Bound To G-9807
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2020-12-09 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SJS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-09
Ligands: SJS
 |
Pcsk9-Fab 7G7 Complex Bound To Cis-1-Amino-4-Phenylcyclohexaneacyl-Wnlk(Hr)Igllr - Nh2
Organism: Homo sapiens, Mus musculus, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2020-02-05 Classification: HYDROLASE/HYDROLASE INHIBITOR/IMMUNE SYSTEM Ligands: CA |
Organism: Homo sapiens, Mus musculus, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-02-05
Ligands: CA
 |
Design Of Organo-Peptides As Bipartite Pcsk9 Antagonists
Organism: Homo sapiens, Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2020-02-05 Classification: HYDROLASE/HYDROLASE INHIBITOR/IMMUNE SYSTEM Ligands: CA |
Organism: Homo sapiens, Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2020-02-05
Ligands: CA
 |
Crystal Structure Of Ire1A In Complex With Compound 18
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2019-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: QFV, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-06
Ligands: QFV, GOL
 |
Taf1-Bd2 In Complex With Cpd27 (6-(But-3-En-1-Yl)-4-(1-Methyl-6-(Morpholine-4-Carbonyl)-1H-Benzo[D]Imidazol-4-Yl)-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One)
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2018-11-14 Classification: Transcription/Inhibitor Ligands: G9V |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2018-11-14
Ligands: G9V
 |
Taf1-Bd2 In Complex With Cpd8 (6-(But-3-En-1-Yl)-4-(3-(Morpholine-4-Carbonyl)Phenyl)-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One)
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2018-10-31 Classification: Transcription/Inhibitor Ligands: G9Y |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2018-10-31
Ligands: G9Y
 |
Crebbp Bromodomain In Complex With Cpd 4 (1-(1-(Cyclopropylmethyl)-3-(1H-Indol-4-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.39 Å Release Date: 2018-08-08 Classification: PROTEIN BINDING/INHIBITOR Ligands: DMS, EDO, BKD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-08
Ligands: DMS, EDO, BKD