Search Count: 12
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Crystal Structure Of Kras-G12D (Gdp-Bound) In Complex With Bbo-11818
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2025-12-03 Classification: ONCOPROTEIN/INHIBITOR Ligands: GDP, MG, A1CG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-12-03
Ligands: GDP, MG, A1CG4
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Crystal Structure Of Kras-G12D (Gmppnp-Bound) In Complex With Bbo-11818
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2025-12-03 Classification: ONCOPROTEIN/INHIBITOR Ligands: GNP, MG, A1CG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-12-03
Ligands: GNP, MG, A1CG4
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Crystal Structure Of Hras-G12D/Q95H (Gmppnp-Bound) In Complex With Bbo-11818
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2025-12-03 Classification: ONCOPROTEIN Ligands: GNP, MG, A1CG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-12-03
Ligands: GNP, MG, A1CG4
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Crystal Structure Of P110Alpha-Rbd Covalently Bound To A Breaker Compound Bbo-10203 Via Cys242
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2025-06-25 Classification: ONCOPROTEIN Ligands: A1AIR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-06-25
Ligands: A1AIR
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Crystal Structure Of Active Kras-G12C (Gmppnp-Bound) In Complex With Bbo-8520
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2024-12-18 Classification: ONCOPROTEIN/INHIBITOR Ligands: GNP, MG, Y8N |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: GNP, MG, Y8N
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Crystal Structure Of Kras-G12C (Gdp-Bound) In Complex With Bbo-8520
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2024-12-18 Classification: ONCOPROTEIN/INHIBITOR Ligands: GDP, MG, Y8N |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: GDP, MG, Y8N
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Co-Crystal Structure Of Perk Bound To N-{5-[(6,7-Dimethoxyquinolin-4-Yl)Oxy]Pyridin-2-Yl}-1-Methyl-3-Oxo-2-Phenyl-5-(Pyridin-4-Yl)-2,3-Dihydro-1H-Pyrazole-4-Carboxamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-02-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z2, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-04
Ligands: 3Z2, SO4
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Co-Crystal Structure Of Perk With 2-Amino-N-[4-Methoxy-3-(Trifluoromethyl)Phenyl]-4-Methyl-3-[2-(Methylamino)Quinazolin-6-Yl]Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z1, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z1, TLA
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Co-Crystal Structure Of Perk Bound To 4-{2-Amino-3-[5-Fluoro-2-(Methylamino)Quinazolin-6-Yl]-4-Methylbenzoyl}-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3H-Pyrazol-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z3, TLA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z3, TLA, GOL
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Co-Crystal Structure Of Perk Bound To 4-{2-Amino-4-Methyl-3-[2-(Methylamino)-1,3-Benzothiazol-6-Yl]Benzoyl}-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3H-Pyrazol-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z4, TLA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z4, TLA, GOL
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Co-Crystal Structure Of Perk Bound To 4-[2-Amino-4-Methyl-3-(2-Methylquinolin-6-Yl)Benzoyl]-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3H-Pyrazol-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z5, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z5, TLA
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Co-Crystal Structure Of Perk Bound To 1-[5-(4-Amino-2,7-Dimethyl-7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)-2,3-Dihydro-1H-Indol-1-Yl]-2-[3-Fluoro-5-(Trifluoromethyl)Phenyl]Ethanone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z6