Search Count: 11
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Egfr (L858R, T790M, V948R) In Complex With N-{3-[(2-{[4-(4-Methylpiperazin-1-Yl)Phenyl]Amino}-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Oxy]Phenyl}Prop-2-Enamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.52 Å Release Date: 2016-02-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 633, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: 633, SO4, GOL
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Egfr (L858R, T790M, V948R) In Complex With N-[3-({2-[(1-Methyl-1H-Pyrazol-4-Yl)Amino]-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl}Oxy)Phenyl]Prop-2-Enamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.42 Å Release Date: 2016-02-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 634, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: 634, SO4, GOL
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Egfr (L858R, T790M, V948R) In Complex With 1-[(3R,4R)-3-[({2-[(1-Methyl-1H-Pyrazol-4-Yl)Amino]-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl}Oxy)Methyl]-4-(Trifluoromethyl)Pyrrolidin-1-Yl]Prop-2-En-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2016-02-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 63A, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: 63A, SO4, GOL
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Egfr (L858R, T790M, V948R) In Complex With 1-{(3R,4R)-3-[5-Chloro-2-(1-Methyl-1H-Pyrazol-4-Ylamino)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yloxymethyl]-4-Methoxy-Pyrrolidin-1-Yl}Propenone (Pf-06459988)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2016-01-27 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 630, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: 630, SO4
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Catalytic Unit Of Pi3Kg In Complex With Pi3K/Mtor Dual Inhibitor Pf-04979064
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-11-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 19P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-20
Ligands: 19P
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Inhibitor Bound Structure Of The Kinase Domain Of The Murine Receptor Tyrosine Kinase Tyro3 (Sky)
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-03-13 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0T8 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2013-03-13
Ligands: 0T8
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Inhibitor Bound Structure Of The Kinase Domain Of The Murine Receptor Tyrosine Kinase Tyro3 (Sky)
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-03-13 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 14S |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2013-03-13
Ligands: 14S
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Discovery Of A Novel, Potent And Selective Inhibitor Of 3-Phosphoinositide Dependent Kinase (Pdk1)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2011-11-16 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: GOL, SO4, ABQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-16
Ligands: GOL, SO4, ABQ
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Discovery Of A Novel, Potent And Selective Inhibitor Of 3-Phosphoinositide Dependent Kinase (Pdk1)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2011-11-16 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3RW, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-16
Ligands: 3RW, GOL, SO4
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Discovery Of The Highly Potent Pi3K/Mtor Dual Inhibitor Pf-04691502 Through Structure Based Drug Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2010-06-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ML8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-06-02
Ligands: ML8
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Discovery Of The Highly Potent Pi3K/Mtor Dual Inhibitor Pf-04691502 Through Structure Based Drug Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2010-06-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ML9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-06-02
Ligands: ML9