Search Count: 5
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Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With (2S)-2-((3R)-3-Acetamido-3-Isobutyl-2-Oxo-1-Pyrrolidinyl)-N-((1S,2R)-1-(3,5-Difluorobenzyl)-2-Hydroxy-2-(1,2,3,4-Tetrahydro-3-Isoquinolinyl)Ethyl)-4-Phenylbutanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.88 Å Release Date: 2011-09-07 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: PB8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-09-07
Ligands: PB8
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Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With Bms-693391 Aka (2S)-2-((3R)-3-Acetamido-3-Isobutyl-2-Oxo-1-Pyrrolidinyl)-N-((1S,2R)-1-(3,5-Difluorobenzyl)-2-Hydroxy-2-((2R,4R)-4-Propoxy-2-Pyrrolidinyl)Ethyl)-4-Phenylbutanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2011-08-31 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: PB0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-31
Ligands: PB0
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Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With (2S)-2-((3S)-3-(Acetylamino)-3-(Butan-2-Yl)-2-Oxopyrrolidin-1-Yl)-N-((2S,3R)-3-Hydroxy-4-((3-Methoxybenzyl)Amino)-1-Phenylbutan-2-Yl)-4-Phenylbutanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2011-08-31 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: PB7, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-31
Ligands: PB7, IOD
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Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With Bms-655295 Aka N~3~-((1S,2R)-1- Benzyl-2-Hydroxy-3-((3-Methoxybenzyl)Amino)Propyl)-N~1~, N~1~-Dibutyl-1H-Indole-1,3-Dicarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2011-04-06 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 3HF, IOD, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-06
Ligands: 3HF, IOD, GOL
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Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With Bms-681889 Aka N~1~-Butyl-5-Cyano- N~3~-((1S,2R)-1-(3,5-Difluorobenzyl)-2-Hydroxy-3-((3- Methoxybenzyl)Amino)Propyl)-N~1~-Methyl-1H-Indole-1,3- Dicarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2011-04-06 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 3HH, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-06
Ligands: 3HH, SO4, GOL