Search Count: 20
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Structure Of Human Klk5 Bound To Anti-Klk5 Fab
Organism: Synthetic construct, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2022-12-14 Classification: HYDROLASE/IMMUNE SYSTEM Ligands: SO4 |
Organism: Synthetic construct, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-12-14
Ligands: SO4
 |
Identification Of An Imidazopyridine Scaffold To Generate Potent And Selective Tyk2 Inhibitors That Demonstrate Activity In An In Vivo Psoriasis Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2017-09-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9ZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: 9ZS
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Identification Of An Imidazopyridine Scaffold To Generate Potent And Selective Tyk2 Inhibitors That Demonstrate Activity In An In Vivo Psoriasis Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2017-09-06 Classification: Transferase/Transferase Inhibitor Ligands: 9ZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: 9ZS
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Crystal Structure Of Fab 39.29 In Complex With Influenza Hemagglutinin A/Perth/16/2009 (H3N2)
Organism: Influenza a virus, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2013-08-07 Classification: IMMUNE SYSTEM Ligands: NAG, PO4, PGE |
Organism: Influenza a virus, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-07
Ligands: NAG, PO4, PGE
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-4-Cyano-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0X6
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-N-[2-({[(1R,2R)-2-Fluorocyclopropyl]Carbonyl}Amino)Pyridin-4-Yl]Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0XH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0XH
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-4-Cyano-N-[2-({[(1R,2R)-2-Fluorocyclopropyl]Carbonyl}Amino)Pyridin-4-Yl]Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0XP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0XP
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Jak2 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-[(8As)-2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(8Ah)-Yl]Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
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Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
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Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor (Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexyl)Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J6
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Jak1 Kinase (Jh1 Domain) In Complex With Compound 34
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 15T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 15T
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Potent And Highly Selective Benzimidazole Inhibitors Of Pi3K-Delta
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2012-08-22 Classification: transferase/transferase inhibitor Ligands: 0WR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-22
Ligands: 0WR
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The Jak1 Kinase Domain In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2012-07-04 Classification: Transferase/Transferase Inhibitor Ligands: JAK, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: JAK, EDO
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Jak1 Kinase (Jh1 Domain) In Complex With Compound 20
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0Q2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: 0Q2
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Discovery And Optimization Of C-2 Methyl Imidazo-Pyrrolopyridines As Potent And Orally Bioavailable Jak1 Inhibitors With Selectivity Over Jak2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1RS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: 1RS
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Discovery And Optimization Of C-2 Methyl Imidazo-Pyrrolopyridines As Potent And Orally Bioavailable Jak1 Inhibitors With Selectivity Over Jak2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: JAK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: JAK
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Crystal Structure Of Bruton'S Tyrosine Kinase In Complex With Inhibitor Cgi1746
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2010-11-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, BME, 746 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-11-03
Ligands: SO4, BME, 746
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Crystal Structure Of Bruton'S Tyrosine Kinase Mutant V555R In Complex With Dasatinib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2010-11-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1N1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-11-03
Ligands: 1N1
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Crystal Structure Of The Human Btk Kinase Domain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2010-11-03 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-11-03
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M1Prime Peptide From Ige Bound By Humanized Antibody 47H4 Fab
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2010-05-19 Classification: IMMUNE SYSTEM Ligands: GOL |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2010-05-19
Ligands: GOL