Search Count: 49
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Myeloid Cell Leukemia-1 (Mcl-1) Complexed With Compound 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2025-09-17 Classification: APOPTOSIS Ligands: A1CL3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-09-17
Ligands: A1CL3
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Myeloid Cell Leukemia-1 (Mcl-1) Complexed With Compound 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2025-09-17 Classification: APOPTOSIS Ligands: A1CL6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-09-17
Ligands: A1CL6
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Structure Of 1 In Complex With Gdp-Kras
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.18 Å Release Date: 2025-08-06 Classification: HYDROLASE Ligands: GDP, MG, EDO, A1I1P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-08-06
Ligands: GDP, MG, EDO, A1I1P
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Structure Of 5 In Complex With Gdp-Kras
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.00 Å Release Date: 2025-08-06 Classification: HYDROLASE Ligands: GDP, MG, EDO, A1I1R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-08-06
Ligands: GDP, MG, EDO, A1I1R
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Structure Of 10 In Complex With Gdp-Kras
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:0.95 Å Release Date: 2025-08-06 Classification: HYDROLASE Ligands: GDP, MG, EDO, WYU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-08-06
Ligands: GDP, MG, EDO, WYU
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Structure Of 12 In Complex With Gdp-Kras
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.06 Å Release Date: 2025-08-06 Classification: HYDROLASE Ligands: GDP, MG, EDO, A1I1Z |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-08-06
Ligands: GDP, MG, EDO, A1I1Z
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Structure Of 18 (Bi-2493) In Complex With Gdp-Kras
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.01 Å Release Date: 2025-08-06 Classification: HYDROLASE Ligands: GDP, MG, EDO, VU6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-08-06
Ligands: GDP, MG, EDO, VU6
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Identification Of Multiple Ligand Hotspots On Sos2, Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1ASY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1ASY
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Identification Of Multiple Ligand Hotspots On Sos2, Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1ASX, DMS, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1ASX, DMS, SO4
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Identification Of Multiple Ligand Hotspots On Sos2, Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1ASW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1ASW
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Sos2 In Complex With Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2025-02-05 Classification: HYDROLASE Ligands: A1IL1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1IL1
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Myeloid Cell Leukemia-1 (Mcl-1) Complexed With Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2024-08-07 Classification: APOPTOSIS Ligands: A1ALT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-07
Ligands: A1ALT
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Expanding The Chemical Landscape Of Sos1 Activators Using Fragment Based Methods
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2020-08-26 Classification: SIGNALING PROTEIN Ligands: GNP, MG, QTV, FMT, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-26
Ligands: GNP, MG, QTV, FMT, GOL, NA
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Expanding The Chemical Landscape Of Sos1 Activators Using Fragment Based Methods
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2020-08-26 Classification: SIGNALING PROTEIN Ligands: GNP, MG, FMT, QTS, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-26
Ligands: GNP, MG, FMT, QTS, GOL, NA
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Expanding The Chemical Landscape Of Sos1 Activators Using Fragment Based Methods
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2020-08-26 Classification: SIGNALING PROTEIN Ligands: GNP, MG, QTM, FMT, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-26
Ligands: GNP, MG, QTM, FMT, GOL, NA
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Expanding The Chemical Landscape Of Sos1 Activators Using Fragment Based Methods
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2020-08-26 Classification: SIGNALING PROTEIN Ligands: GNP, MG, ACT, QTJ, FMT, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-26
Ligands: GNP, MG, ACT, QTJ, FMT, GOL, NA
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Expanding The Chemical Landscape Of Sos1 Activators Using Fragment Based Methods
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2020-08-26 Classification: SIGNALING PROTEIN Ligands: GNP, MG, QTG, FMT, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-26
Ligands: GNP, MG, QTG, FMT, GOL, NA
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Expanding The Chemical Landscape Of Sos1 Activators Using Fragment Based Methods
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2020-08-26 Classification: SIGNALING PROTEIN Ligands: GNP, MG, FMT, QTD, GOL, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-26
Ligands: GNP, MG, FMT, QTD, GOL, NA
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Discovery Of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate In Vivo Activity In Mouse Xenograft Models Of Human Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2019-04-17 Classification: APOPTOSIS Ligands: KJP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-17
Ligands: KJP
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Ras:Sos:Ras In Complex With A Small Molecule Activator
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2019-03-27 Classification: SIGNALING PROTEIN Ligands: MG, GNP, FVV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-27
Ligands: MG, GNP, FVV