Search Count: 12
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2019-11-27 Classification: TRANSCRIPTION Ligands: L5B |
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Organism: Saccharomyces cerevisiae
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-12-10 Classification: RNA BINDING PROTEIN Ligands: SO4 |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.99 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: EUT |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, RBQ |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2014-11-26 Classification: TRANSFERASE |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.83 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, GOL, UJB |
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Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, 7A5 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2014-10-22 Classification: LIPID KINASE Ligands: SO4, 1TT |
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Discovery And Optimization Of Pyrimidone Indoline Amide Pi3Kbeta Inhibitors For The Treatment Of Phosphatase And Tensin Homologue (Pten)-Deficient Cancers
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-01-15 Classification: TRANSFERASE Ligands: J82 |
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X-Ray Structure Of Pi3K-Gamma Bound To A 4-(Morpholin-4-Yl)- (6-Oxo-1,6-Dihydropyrimidin-2-Yl)Amide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.40 Å Release Date: 2012-11-14 Classification: Transferase/Transferase Inhibitor Ligands: 0W7 |
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Discovery And Optimization Of New Benzimidazole- And Benzoxazole-Pyrimidone Selective Pi3Kbeta Inhibitors For The Treatment Of Phosphatase And Tensin Homologue (Pten)-Deficient Cancers
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2012-05-16 Classification: TRANSFERASE Ligands: VWN |
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Human Unphosphorylated Igf1-R Kinase Domain In Complex With An Hydantoin Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2011-05-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: MQY |