Search Count: 12
 |
Estrogen Receptor Mutant L536S
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2019-11-27 Classification: TRANSCRIPTION Ligands: L5B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-27
Ligands: L5B
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.99 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: EUT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: EUT
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, RBQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: SO4, RBQ
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2014-11-26 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.83 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, GOL, UJB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: SO4, GOL, UJB
 |
Discovery Of (2S)-8-((3R)-3-Methylmorpholin-4-Yl)-1-(3-Methyl-2-Oxo- Butyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido(1,2-A)Pyrimidin-6- One: A Novel Potent And Selective Inhibitor Of Vps34 For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-11-26 Classification: TRANSFERASE Ligands: SO4, 7A5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: SO4, 7A5
 |
Sar156497 An Exquisitely Selective Inhibitor Of Aurora Kinases
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2014-11-19 Classification: TRANSFERASE Ligands: Y3M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-19
Ligands: Y3M
 |
Sar156497 An Exquisitely Selective Inhibitor Of Aurora Kinases
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.20 Å Release Date: 2014-11-19 Classification: TRANSFERASE Ligands: QMN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-19
Ligands: QMN
 |
Sar156497 An Exquisitely Selective Inhibitor Of Aurora Kinases
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2014-11-19 Classification: TRANSFERASE Ligands: JVE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-19
Ligands: JVE
 |
Discovery And Optimization Of Pyrimidone Indoline Amide Pi3Kbeta Inhibitors For The Treatment Of Phosphatase And Tensin Homologue (Pten)-Deficient Cancers
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-01-15 Classification: TRANSFERASE Ligands: J82 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2014-01-15
Ligands: J82
 |
X-Ray Structure Of Pi3K-Gamma Bound To A 4-(Morpholin-4-Yl)- (6-Oxo-1,6-Dihydropyrimidin-2-Yl)Amide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.40 Å Release Date: 2012-11-14 Classification: Transferase/Transferase Inhibitor Ligands: 0W7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-11-14
Ligands: 0W7
 |
Discovery And Optimization Of New Benzimidazole- And Benzoxazole-Pyrimidone Selective Pi3Kbeta Inhibitors For The Treatment Of Phosphatase And Tensin Homologue (Pten)-Deficient Cancers
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2012-05-16 Classification: TRANSFERASE Ligands: VWN |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2012-05-16
Ligands: VWN