| The RANDMARDI procedure of the complete relaxation matrix analysis method, MARDIGRAS, was used to calculate interproton distance bounds from the integrated NOESY cross-peak intensities. These distance bounds were then used as restraints in an RMD procedure to yield 20 structures. |
The structures are based on a total of 524 restraints, 502 are NOE-derived distance constraints and 22 distance restraints from hydrogen bonds. |
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