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S.No. Project ID Project title Principal investigator Description Institute Experiment Type Release Date PubMed-ID
61 IPD3987 The preclinical evaluation of a second-generation antivenom for treating snake envenoming in India Dr. Kartik Sunagar In this study, by employing chromatographic purification of the bulk, we have significantly enhanced the preclinical performance of the conventional Indian antivenom product. The effectiveness of the test batches of this ‘second-generation’ antivenom was evaluated using a variety of in vitro and in vivo preclinical assays, including venom recognition and... Read more Evolutionary Venomics Lab, Center for Ecological Sciences, Indian Institute of Science, Bangalore, India Shotgun proteomics 2024-11-24 35324665
62 IPD8910 A wolf in another wolf’s clothing: Post-genomic regulation dictates venom profiles of medically-important cryptic kraits in India Dr. Kartik Sunagar This study investigates the widespread cryptic Bungarus caeruleus (Comman krait) in India and clinical repercussions of their bits by implementing multidisciplinary approach involving proteomics, transcripomics, and assessment of toxicity and efficacy of currently marketed anivenoms. The study also aims at understanding the evolutionary relationships between these phenotypically simillar kraits. Evolutionary Venomics Lab, Center for Ecological Sciences, Indian Institute of Science, Bangalore, India Shotgun proteomics 2024-11-24 33477742
63 IPD3501 CgSub2 interactome analysis in the presence and absence of CgHog1 MAPK in Candida glabrata Dr Rupinder Kaur The objective of the project is to identify CgSub2-interacting proteins in the presence and absence of CgHog1 MAPK in the pathogenic yeast Candida glabrata, with CgSub2 being an interactor of CgHog1. DBT-Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, India Bottom-up 2024-12-07
64 IPD6501 Interactome analysis of the CgHog1 MAPK under varied-iron conditions in Candida glabrata Dr Rupinder Kaur The objective of the project is to identify proteins that interact with CgHog1 under low-iron, regular-iron and high-iron growth conditions in the pathogenic yeast Candida glabrata. DBT-Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, India Bottom-up 2024-12-07
65 IPD8281 Quantitative secretome profiling of Candida glabrata wild-type and aspartyl protease-deficient strains Dr Rupinder Kaur The project is aimed at deciphering the proteins, which are differentially abundant in the secretome of Candida glabrata wild-type and a mutant strain deleted for eleven cell surface-associated aspartyl-proteases (CgYapsins). DBT-Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, India Shotgun proteomics 2024-12-07
66 IPD6532 Total membrane proteome analysis of Candida glabrata wild-type and eleven CgYapsins-deficient strain Cgyps1-11∆. Dr Rupinder Kaur The project is aimed at characterizing the effect of loss of a family of eleven aspartyl proteases (Cg Yapsins) on the global membrane proteome of Candida glabrata. DBT-Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, India Shotgun proteomics 2024-12-07 35051415
67 IPD3061 Phosphatidylinositol 3-phosphate (PI3P) interactome analysis under varied iron conditions in Candida glabrata. Dr Rupinder Kaur The project is aimed at identifying proteins that interact with PI3P in low-iron, regular-iron and high-iron grown Candida glabrata cells. DBT-Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, India Shotgun proteomics 2024-12-07 37490387
68 IPD8104 Secretome analysis of Candida glabrata wild-type and aspartyl protease-deficient strains Dr Rupinder Kaur The project is aimed at characterizing the secretome of a human opportunistic fungal pathogen Candida glabrata. Additionally, the effect of loss of a family of eleven aspartyl proteases (Cg Yapsins) on the Candida glabrata secretome is studied. DBT-Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, India Shotgun proteomics 2024-12-07 31621333
69 IPD1627 Identification of phosphorylated amino acids in CgSub2 protein in Candida glabrata Dr Rupinder Kaur The objective of the project is to identify the phosphorylated amino acid residues in CgSub2 in the pathogenic yeast Candida glabrata. For this analysis, wild-type cells and mutants lacking CgHog1 MAPK or CgSlt2MAPK or both CgHog1 and CgSlt2 MAPKs were used. DBT-Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, India Bottom-up 2024-12-07
70 IPD6103 Interactome identification of Histones H3 and H4 in the presence and absence of methyl methanesulfonate (MMS) in the pathogenic yeast Candida glabrata Dr. Rupinder Kaur The main goal of this project is to identify proteins in Candida glabrata that interact with histones H3 (CgHht) and H4 (CgHhf) under normal and MMS-treatment conditions. DBT-Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, India Shotgun proteomics 2024-12-07 32134928