ISDA: 9YTQ

Deposition Date 2025-10-21

Release Date 2026-02-25

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9YTQ

Keywords:

DE NOVO PROTEIN

Title:

Computationally Designed Tetramer of Apo-HC4 (C1 symmetry)

Biological Source:

Source Organism(s):

synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.34 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Designed tetrameric HC4 prote
Chain IDs:A, B, C, D
Chain Length:138
Number of Molecules:4
Biological Source:synthetic construct

Ligand Molecules

Primary Citation

Computational Design of a Highly Stable Dicopper Catechol Oxidase.

Eng, V.H, Narehood, S.M, Li, Y, Gascon, M, Hoffnagle, A.M, Shiau, A.A, Semonis, M, Green, M.T, Britt, R.D, Tezcan, F.A.Show

J.Am.Chem.Soc. 148 8361 8373 (2026)

PMID: 41707222 DOI: 10.1021/jacs.5c18979

Primary Citation of related structures

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