9YRC image
Deposition Date 2025-10-16
Release Date 2026-03-25
Last Version Date 2026-03-25
Entry Detail
PDB ID:
9YRC
Keywords:
TRANSLOCASE
Title:
p97Ufd1-Npl4 complex processing poly-ubiquitinated substrate in the presence of ATP
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Saccharomyces cerevisiae (Taxon ID: 4932)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.97 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9YRC validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transitional endoplasmic reti
Gene (Uniprot):VCP
Chain IDs:A, B, C, D, E, F
Chain Length:806
Number of Molecules:6
Biological Source:Homo sapiens
UniProt ID:P55072 Pfam ID:PF02359, PF02933, PF00004, PF17862 EC:3.6.4.6
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Nuclear protein localization
Gene (Uniprot):NPLOC4
Chain IDs:G
Chain Length:608
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8TAT6 Pfam ID:PF11543, PF05020, PF05021
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ubiquitin recognition factor
Gene (Uniprot):UFD1
Chain IDs:H
Chain Length:307
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q92890 Pfam ID:PF03152, PF24842
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ubiquitin
Gene (Uniprot):RPL40A
Chain IDs:I
Chain Length:76
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
UniProt ID:P0CH08 Pfam ID:PF00240
Ligand Molecules
ADP
ATP
Primary Citation
The deubiquitinating enzyme Otu1 releases substrates from the conserved initiation complex of the Cdc48/p97 ATPase for proteasomal degradation.
Sci Rep ? ? ? (2026)
PMID: 41795027 DOI: 10.1038/s41598-026-42811-6
Primary Citation of related structures
9YRC
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