ISDA: 9YI2

Deposition Date 2025-10-01

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9YI2

Keywords:

DNA BINDING PROTEIN

Title:

Human EEPD1 EEP domain dimer

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Endonuclease/exonuclease/phos
Chain IDs:A, B
Chain Length:590
Number of Molecules:2
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

EEPD1 evolved a unique DNA clamping dimer protecting reversed replication forks

Shen, R, Sarker, A.H, Chen, Y, Liu, M, Roy, S, Arvai, A.S, Bacolla, A, Ahmed, Z, Katsonis, P, Hammel, M, Kuraoka, I, Tsai, M, Irie, C, Webb, L, Lichtarge, O, Tsai, C, Tsutakawa, S.E, Schlacher, K, Tainer, J.Show

Nucleic Acids Res. 54 ? ? (2026)

PMID: 41830330 DOI: 10.1093/nar/gkag188

Primary Citation of related structures

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