ISDA: 9WBG

Deposition Date 2025-08-14

Release Date 2026-04-01

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9WBG

Keywords:

HYDROLASE

Title:

Structure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl and Catch domain resolved

Biological Source:

Source Organism(s):

Escherichia coli K-12 (Taxon ID: 83333)
Homo sapiens (Taxon ID: 9606)
Pseudotamlana agarivorans (Taxon ID: 481183)

Expression System(s):

Escherichia coli k-12

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.23 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:26S proteasome regulatory sub
Chain IDs:P (auth: A)
Chain Length:376
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome regulatory sub
Chain IDs:Q (auth: B)
Chain Length:377
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome regulatory sub
Chain IDs:B (auth: C)
Chain Length:590
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome regulatory sub
Chain IDs:C (auth: D)
Chain Length:350
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome regulatory sub
Chain IDs:R (auth: E)
Chain Length:70
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome regulatory sub
Chain IDs:S (auth: F)
Chain Length:439
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Chain IDs:N (auth: U)
Chain Length:953
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Chain IDs:D (auth: V)
Chain Length:534
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Chain IDs:E (auth: W)
Chain Length:337
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Chain IDs:F (auth: X)
Chain Length:422
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Chain IDs:G (auth: Y)
Chain Length:389
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Chain IDs:H (auth: Z)
Chain Length:324
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Chain IDs:I (auth: a)
Chain Length:376
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Chain IDs:J (auth: b)
Chain Length:377
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Ubiquitin C-terminal hydrolas
Chain IDs:O (auth: c)
Chain Length:590
Number of Molecules:1
Biological Source:Homo sapiens, Pseudotamlana agarivorans

Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Chain IDs:K (auth: d)
Chain Length:350
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:26S proteasome complex subuni
Chain IDs:L (auth: e)
Chain Length:70
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Maltose/maltodextrin-binding
Chain IDs:A (auth: f)
Chain Length:439
Number of Molecules:1
Biological Source:Escherichia coli K-12, Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Substrate
Chain IDs:M (auth: v)
Chain Length:534
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Early growth response protein
Chain IDs:T (auth: w)
Chain Length:337
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules