9VJL image
Deposition Date 2025-06-20
Release Date 2026-03-25
Last Version Date 2026-03-25
Entry Detail
PDB ID:
9VJL
Keywords:
APOPTOSIS
Title:
Phosphorylation dependent recognition of RIPK1 by phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
Biological Source:
Source Organism(s):
Mus musculus (Taxon ID: 10090)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
SOLUTION NMR
Conformers Calculated:
200
Conformers Submitted:
20
Selection Criteria:
structures with the lowest energy
9VJL validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Phosphatidylinositol 3,4,5-tr
Gene (Uniprot):Inpp5d
Chain IDs:A
Chain Length:106
Number of Molecules:1
Biological Source:Mus musculus
UniProt ID:Q9ES52 Pfam ID:PF00017
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Receptor-interacting serine/t
Gene (Uniprot):Ripk1
Chain IDs:B
Chain Length:16
Number of Molecules:1
Biological Source:Mus musculus
UniProt ID:Q60855 EC:2.7.10.2
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
PTR B TYR modified residue
Ligand Molecules
NA
Primary Citation
Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer's disease risk factors.
Immunity 59 419 437.e11 (2026)
PMID: 41633359 DOI: 10.1016/j.immuni.2026.01.014
Primary Citation of related structures
9VJL
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