ISDA: 9V3S

Deposition Date 2025-05-22

Release Date 2026-04-01

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9V3S

Keywords:

MEMBRANE PROTEIN

Title:

Nav1.5 in complex with quinidine-azo

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.00 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Sodium channel protein type 5
Gene (Uniprot):SCN5A
Chain IDs:A
Chain Length:1618
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q14524 Pfam ID:PF00520, PF06512

Ligand Molecules

A1EQU

NAG

Primary Citation

Optical control of the cardiac rhythm with photoswitchable Na V 1.5 channel blockers.

Liu, S, Guan, W, Li, Z, Wang, W, Song, H, Li, J, Hou, J, Wang, H, Xiong, J, Yang, M, Yan, N, Tian, X, Li, H, Huang, Z.Show

Nat Commun ? ? ? (2026)

PMID: 41807386 DOI: 10.1038/s41467-026-70305-6

Primary Citation of related structures

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