ISDA: 9TKM

Deposition Date 2025-12-10

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9TKM

Keywords:

VIRUS LIKE PARTICLE

Title:

CryoEM structure of coxsackievirus B1 virus-like particle with VP4 deletion

Biological Source:

Source Organism(s):

Coxsackievirus B1 (Taxon ID: 12071)

Expression System(s):

Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.70 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Capsid protein VP1
Chain IDs:A (auth: 1)
Chain Length:278
Number of Molecules:1
Biological Source:Coxsackievirus B1

UniProt ID:P08291

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Capsid protein VP2
Chain IDs:B (auth: 2)
Chain Length:263
Number of Molecules:1
Biological Source:Coxsackievirus B1

UniProt ID:P08291

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Capsid protein VP3
Chain IDs:C (auth: 3)
Chain Length:238
Number of Molecules:1
Biological Source:Coxsackievirus B1

UniProt ID:P08291

Ligand Molecules

Primary Citation

Coxsackie B1 virus-like particle that lacks VP4 protein demonstrates improved vaccine scalability, stability and immunogenicity.

Soppela, S, Kyrolainen, H.M, Levanova, A, Nekoua, M.P, Gonzalez-Rodriguez, M, Lehto, H, Ahmad, K.L.L, Guryanov, S, Hytonen, V.P, Laitinen, O.H, Junttila, I.S, Hober, D, Butcher, S.J, Hankaniemi, M.M.Show

J.Biomed.Sci. 33 ? ? (2026)

PMID: 41888844 DOI: 10.1186/s12929-026-01229-y

Primary Citation of related structures

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