9T93 image
Deposition Date 2025-11-13
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9T93
Keywords:
Title:
cryo-EM structure of autophosphorylated mTOR complex 2, focused on a single protomer
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.86 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Serine/threonine-protein kina
Gene (Uniprot):MTOR
Chain IDs:A
Chain Length:2590
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Target of rapamycin complex s
Gene (Uniprot):MLST8
Chain IDs:B (auth: C)
Chain Length:326
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Rapamycin-insensitive compani
Gene (Uniprot):RICTOR
Chain IDs:C (auth: E)
Chain Length:1734
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Target of rapamycin complex 2
Gene (Uniprot):MAPKAP1
Chain IDs:D (auth: G)
Chain Length:522
Number of Molecules:1
Biological Source:Homo sapiens
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
SEP D SER modified residue
Primary Citation
Structural basis for a phosphoinositide-driven mTORC2-AKT positive feedback loop
Biorxiv ? ? ? (2026)
DOI: 10.64898/2026.01.08.698367
Primary Citation of related structures
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