ISDA: 9T5Z

Deposition Date 2025-11-06

Release Date 2026-03-25

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9T5Z

Keywords:

IMMUNE SYSTEM

Title:

Cryo-EM structure of alphaM/beta2:MEM148-Fab headpiece complex (without alphaM I-domain)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)

Expression System(s):

Homo sapiens, Mus musculus

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.10 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Integrin alpha-M
Gene (Uniprot):ITGAM
Chain IDs:A
Chain Length:762
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P11215 Pfam ID:PF00092, PF01839, PF08441

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Integrin beta-2
Gene (Uniprot):ITGB2
Chain IDs:B
Chain Length:469
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P05107 Pfam ID:PF17205, PF00362

Polymer Type:polypeptide(L)
Molecule:Murine IgG1 MEM148 heavy chai
Chain IDs:C (auth: H)
Chain Length:218
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:Anti-colorectal carcinoma lig
Chain IDs:D (auth: L)
Chain Length:214
Number of Molecules:1
Biological Source:Mus musculus

Ligand Molecules