9SWN image
Deposition Date 2025-10-07
Release Date 2026-04-08
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9SWN
Keywords:
RNA BINDING PROTEIN
Title:
Cryo-EM structure of yeast telomerase holoenzyme
Biological Source:
Source Organism(s):
Saccharomyces cerevisiae (Taxon ID: 4932)
Expression System(s):
Saccharomyces cerevisiae
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.00 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9SWN validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Telomerase reverse transcript
Chain IDs:G (auth: A)
Chain Length:884
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Polymer Type:polyribonucleotide
Molecule:TLC1 RNA
Chain IDs:F (auth: B)
Chain Length:1157
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:Telomere replication protein
Chain IDs:A (auth: C)
Chain Length:181
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:Ribonucleases P/MRP protein s
Chain IDs:E (auth: D)
Chain Length:875
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:Ribonucleases P/MRP protein s
Chain IDs:B (auth: E)
Chain Length:158
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:Ribonucleases P/MRP protein s
Chain IDs:D (auth: F)
Chain Length:140
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:Telomere elongation protein E
Chain IDs:C (auth: G)
Chain Length:699
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Ligand Molecules
MG
ZN
Primary Citation
Cryo-electron microscopy structure of the budding yeast telomerase holoenzyme.
Science 391 eadz5344 eadz5344 (2026)
PMID: 41886584 DOI: 10.1126/science.adz5344
Primary Citation of related structures
9SWN
Feedback Form
Name
Email
Institute
Feedback