9SOQ image
Deposition Date 2025-09-15
Release Date 2025-09-24
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9SOQ
Keywords:
HYDROLASE
Title:
Tissue inhibitor of Metalloproteinase 1 (TIMP-1)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.30 Å
R-Value Free:
0.26
R-Value Work:
0.21
Space Group:
P 1 21 1
9SOQ validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Metalloproteinase inhibitor 1
Gene (Uniprot):TIMP1
Chain IDs:A, B
Chain Length:184
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P01033 Pfam ID:PF00965 EC:3.4.24.22
Ligand Molecules
FLC
Primary Citation
The human TIMP-1 unbound structure provides a platform for fragment screening.
Acta Crystallogr D Struct Biol ? ? ? (2026)
PMID: 41834537 DOI: 10.1107/S2059798326001749
Primary Citation of related structures
9SOQ
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