ISDA: 9S6T

Deposition Date 2025-08-01

Release Date 2026-03-18

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9S6T

Keywords:

TRANSFERASE

Title:

Ternary cryo-EM structure of chicken ALG12 with Dol25-PP-GlcNAc2Man7, Dol25-P-Man, and Fab

Biological Source:

Source Organism(s):

Gallus gallus (Taxon ID: 9031)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Homo sapiens, Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.42 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Mannosyltransferase
Mutagens:E35Q
Chain IDs:A
Chain Length:496
Number of Molecules:1
Biological Source:Gallus gallus

Polymer Type:polypeptide(L)
Molecule:Gg12-11 Fab heavy chain
Chain IDs:B (auth: H)
Chain Length:234
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polypeptide(L)
Molecule:Gg12-11 Fab light chain
Chain IDs:C (auth: L)
Chain Length:215
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules