ISDA: 9R9B

Deposition Date 2025-05-19

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9R9B

Keywords:

CELL CYCLE

Title:

Crystal structure of clathrin heavy chain in complex with a peptidomimetic inhibitor of the TACC3 interaction

Biological Source:

Source Organism(s):

Rattus norvegicus (Taxon ID: 10116)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.15 Å

R-Value Free:

0.26

R-Value Work:

0.20

Space Group:

P 61 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Clathrin heavy chain 1
Gene (Uniprot):Cltc
Chain IDs:A
Chain Length:574
Number of Molecules:1
Biological Source:Rattus norvegicus

UniProt ID:P11442 Pfam ID:PF01394, PF09268, PF13838

Polymer Type:polypeptide(L)
Molecule:SP-TACC3
Chain IDs:B
Chain Length:21
Number of Molecules:1
Biological Source:Homo sapiens

Primary Citation

Development of a peptidomimetic inhibitor of the TACC3/clathrin interaction on the mitotic spindle

Gunning, V, Bayliss, R.Show

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Primary Citation of related structures

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