9QFN image
Deposition Date 2025-03-12
Release Date 2026-03-25
Last Version Date 2026-03-25
Entry Detail
PDB ID:
9QFN
Keywords:
CELL CYCLE
Title:
Crystal structure of T2R-TTL-Li5 complex
Biological Source:
Source Organism(s):
Rattus norvegicus (Taxon ID: 10116)
Gallus gallus (Taxon ID: 9031)
Bos taurus (Taxon ID: 9913)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.25 Å
R-Value Free:
0.25
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 21 21 21
9QFN validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tubulin alpha-1B chain
Chain IDs:A, C
Chain Length:451
Number of Molecules:2
Biological Source:Bos taurus
UniProt ID:P81947 Pfam ID:PF00091, PF03953
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tubulin beta-2B chain
Gene (Uniprot):TUBB2B
Chain IDs:B, D
Chain Length:445
Number of Molecules:2
Biological Source:Bos taurus
UniProt ID:Q6B856 Pfam ID:PF00091, PF03953
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Stathmin-4
Gene (Uniprot):Stmn4
Chain IDs:E
Chain Length:189
Number of Molecules:1
Biological Source:Rattus norvegicus
UniProt ID:P63043 Pfam ID:PF00836
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tubulin tyrosine ligase
Gene (Uniprot):TTL
Chain IDs:F
Chain Length:384
Number of Molecules:1
Biological Source:Gallus gallus
UniProt ID:A0A8V0Z8P0 Pfam ID:PF03133
Ligand Molecules
A1I6L
ACP
CA
CL
GDP
GOL
GTP
IMD
MES
MG
Primary Citation
Phenotypic-screening identifies a new class of cytoskeleton inhibitor with activity in diffuse large B cell lymphoma with functional BCR
To Be Published ? ? ? (?)
Primary Citation of related structures
9QFN
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