9PF9 image
Deposition Date 2025-07-03
Release Date 2025-12-24
Last Version Date 2026-03-04
Entry Detail
PDB ID:
9PF9
Keywords:
IMMUNE SYSTEM
Title:
X-ray crystal structure of ATX-350-2 Fab bound to Epstein-Barr virus glycoprotein 350
Biological Source:
Source Organism(s):
Mus musculus (Taxon ID: 10090)
human gammaherpesvirus 4 (Taxon ID: 10376)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.93 Å
R-Value Free:
0.28
R-Value Work:
0.24
R-Value Observed:
0.24
Space Group:
P 43 21 2
9PF9 validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:BLLF1
Gene (Uniprot):BLLF1
Chain IDs:C (auth: G)
Chain Length:470
Number of Molecules:1
Biological Source:human gammaherpesvirus 4
UniProt ID:A0A0C7T6S7 Pfam ID:PF05109, PF20676, PF20677, PF20678
Polymer Type:polypeptide(L)
Molecule:Fab ATX-350-2 heavy chain
Chain IDs:B (auth: H)
Chain Length:220
Number of Molecules:1
Biological Source:Mus musculus
Polymer Type:polypeptide(L)
Molecule:Fab ATX-350-2 light chain
Chain IDs:A (auth: L)
Chain Length:214
Number of Molecules:1
Biological Source:Mus musculus
Ligand Molecules
NAG
Primary Citation
Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development.
Cell Rep Med 7 102618 102618 (2026)
PMID: 41707657 DOI: 10.1016/j.xcrm.2026.102618
Primary Citation of related structures
9PF9
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