9OVV image
Deposition Date 2025-05-31
Release Date 2026-04-08
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9OVV
Keywords:
MEMBRANE PROTEIN
Title:
Heteromeric GluA1/A2-CNIH1 in the activated state, composite map of LBD-TMD
Biological Source:
Source Organism(s):
Rattus norvegicus (Taxon ID: 10116)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.76 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9OVV validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Isoform Flip of Glutamate rec
Chain IDs:A, C
Chain Length:431
Number of Molecules:2
Biological Source:Rattus norvegicus
Polymer Type:polypeptide(L)
Molecule:Isoform Flip of Glutamate rec
Chain IDs:B, D
Chain Length:428
Number of Molecules:2
Biological Source:Rattus norvegicus
Polymer Type:polypeptide(L)
Molecule:Protein cornichon homolog 1
Chain IDs:E, F, G, H
Chain Length:142
Number of Molecules:4
Biological Source:Homo sapiens
Ligand Molecules
FWF
GLU
NA
POV
Primary Citation
Auxiliary subunits reshape structural asymmetry and functional plasticity in heterotetrameric GluA1/A2 AMPA receptor core.
Nat Commun ? ? ? (2026)
PMID: 41904128 DOI: 10.1038/s41467-026-71063-1
Primary Citation of related structures
9OVV
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