ISDA: 9NYB

Deposition Date 2025-03-27

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9NYB

Keywords:

TRANSFERASE/RNA

Title:

Crystal structure of the pre-reactive state of porcine OAS1 in complex with dsRNA, two ApCpp substrate analogs, three catalytic Mn2+ ions.

Biological Source:

Source Organism(s):

Sus scrofa (Taxon ID: 9823)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.60 Å

R-Value Free:

0.21

R-Value Work:

0.15

Space Group:

P 43 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:2'-5'-oligoadenylate synthase
Gene (Uniprot):OAS1
Chain IDs:A
Chain Length:357
Number of Molecules:1
Biological Source:Sus scrofa

UniProt ID:Q29599 Pfam ID:PF01909, PF10421 EC:2.7.7.84

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(*GP*GP*CP*UP*UP*UP*
Chain IDs:B
Chain Length:19
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(*UP*UP*CP*AP*UP*AP*
Chain IDs:C
Chain Length:19
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules