9NVW image
Deposition Date 2025-03-21
Release Date 2026-04-01
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9NVW
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Cryo-EM structure of rhesus antibody CH35-Apex1.08 in complex with HIV Env trimer Q23-APEX-GT2
Biological Source:
Source Organism(s):
Macaca mulatta (Taxon ID: 9544)
Human immunodeficiency virus 1 (Taxon ID: 11676)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.30 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9NVW validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:CH35-Apex1.08 heavy chain
Chain IDs:A (auth: H)
Chain Length:246
Number of Molecules:1
Biological Source:Macaca mulatta
Polymer Type:polypeptide(L)
Molecule:CH35-Apex1.08 kappa chain
Chain IDs:B (auth: L)
Chain Length:214
Number of Molecules:1
Biological Source:Macaca mulatta
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:HIV envelope gp120
Gene (Uniprot):env
Chain IDs:C (auth: b), E (auth: d), G (auth: f)
Chain Length:478
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1
UniProt ID:O55774
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:HIV envelope gp41 ectodomain
Gene (Uniprot):env
Chain IDs:D (auth: c), F (auth: e), H (auth: g)
Chain Length:153
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1
UniProt ID:O55774
Ligand Molecules
NAG
Primary Citation
Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques
To Be Published ? ? ? (?)
Primary Citation of related structures
9NVW
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