9MRS image
Deposition Date 2025-01-08
Release Date 2026-03-18
Last Version Date 2026-03-18
Entry Detail
PDB ID:
9MRS
Keywords:
METAL TRANSPORT
Title:
Crystal structure of human MMACHC in complex with MMADHC and B12
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.40 Å
R-Value Free:
0.35
R-Value Work:
0.3
R-Value Observed:
0.3
Space Group:
P 1 21 1
9MRS validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cyanocobalamin reductase / al
Gene (Uniprot):MMACHC
Chain IDs:A, C (auth: B), D (auth: E), F (auth: G)
Chain Length:223
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:Q9Y4U1 Pfam ID:PF16690 EC:2.5.1.151
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cobalamin trafficking protein
Gene (Uniprot):MMADHC
Chain IDs:B (auth: D), E (auth: F), G (auth: C), H
Chain Length:296
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:Q9H3L0 Pfam ID:PF10229
Ligand Molecules
B12
Primary Citation
Structural and Biophysical Characterization of Thiolato-Cobalamin
To Be Published ? ? ? (?)
Primary Citation of related structures
9MRS
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