9MBO image
Deposition Date 2025-03-17
Release Date 2026-03-25
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9MBO
Keywords:
HYDROLASE
Title:
Focused refinement of RPN1 and the C-terminal helix of midnolin in the substrate-engaged human 26S proteasome
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.83 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9MBO validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Midnolin
Gene (Uniprot):MIDN
Chain IDs:A
Chain Length:468
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q504T8 Pfam ID:PF00240
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:26S proteasome non-ATPase reg
Gene (Uniprot):PSMD2
Chain IDs:B
Chain Length:908
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q13200 Pfam ID:PF17781, PF01851, PF18051
Ligand Molecules
NA
Primary Citation
Structural dynamics of the midnolin-proteasome during ubiquitin-independent substrate turnover.
Nat Commun 17 ? ? (2026)
PMID: 41896529 DOI: 10.1038/s41467-026-71002-0
Primary Citation of related structures
9MBO
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