ISDA: 9MAT

Deposition Date 2025-03-14

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9MAT

Keywords:

ISOMERASE

Title:

TopBP1 BRCT 7-8 Domain

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.65 Å

R-Value Free:

0.20

R-Value Work:

0.15

R-Value Observed:

0.16

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA topoisomerase 2-binding p
Gene (Uniprot):TOPBP1
Chain IDs:A
Chain Length:233
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q92547 Pfam ID:PF00533, PF23294

Ligand Molecules

MLA

Primary Citation

Small-Molecule Ligand Screening and Structural Investigation of the TopBP1 BRCT 7-8 Domain

Chen, W, Wang, L, Ruan, K.Show

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