ISDA: 9M53

Deposition Date 2025-03-05

Release Date 2026-02-04

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9M53

Keywords:

ISOMERASE

Title:

Crystal structure of 1L-myo-inositol 1-phosphate synthase 1 from Oryza sativa

Biological Source:

Source Organism(s):

Oryza sativa (Taxon ID: 4530)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.79 Å

R-Value Free:

0.18

R-Value Work:

0.14

R-Value Observed:

0.14

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Inositol-3-phosphate synthase
Gene (Uniprot):RINO1
Chain IDs:A, B, C, D
Chain Length:516
Number of Molecules:4
Biological Source:Oryza sativa

UniProt ID:O64437 Pfam ID:PF07994, PF01658 EC:5.5.1.4

Ligand Molecules

EDO

KPG

NAI

Primary Citation

Chemical inhibition of INO1 reduces phytic acid in rice and wheat grains for enhanced micronutrient bioavailability.

Akabane, T, Kamino, S, Okamura, T, Sugaya, A, Nakamura, M, Ikeda, K, Yonezawa, T, Fukushima, A, Kojima, S, Aoki, Y, Chujo, S, Yamauchi, Y, Shibusawa, R, Ishimaru, K, Nagasaka, S, Katoh, E, Hirotsu, N.Show

Nat Food 7 163 173 (2026)

PMID: 41639471 DOI: 10.1038/s43016-026-01295-3

Primary Citation of related structures

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